A major complication associated with burn injury is delayed wound healing. While healing of the burn injury site is essential, healing of distal injury sites caused by surgical interventions and other processes also is important. The impact of burn injury on healing of these distal wound sites is not understood clearly. To study this, mice were subjected to major burn injury or a sham procedure...

OBJECTIVE To perform a systematic exploration of the phenomenon of mobilization of circulating angiogenic cells (CACs) in an animal model. This phenomenon has been observed in patients with cutaneous burn wounds and may be an important mechanism for vasculogenesis in burn wound healing. DESIGN We used a murine model, in which burn depth can be varied precisely, and a validated culture method ...

background and objectives: vitamin e is a fat-soluble vitamin with antioxidant properties, which prevents tissue damages induced by free radicals by their neutralization. the aim of this study was to determine the effect of vitamin e on burn wound healing in rats. methods: in this study, 16 mature male rats weighing 260±10g were used in two groups of 8 each. after induction of anesthesia and sh...

Immunosuppressant drugs adversely influence the woundhealing process by interacting with some of the inflammatory mediators.1 Thus, immunosuppressive therapy may seriously aggravate the clinical course of a burned patient. Most importantly, it predisposes them to infection and by impairing wound healing complicates permanent wound coverage.1 We hereby present the successful treatment of a liver...

A response to Struck MF. Infection control in burn patients: are fungal infections underestimated? Scand J Trauma Resusc Emerg Med. 2009 Oct 9;17(1):51. [Epub ahead of print] PubMed PMID: 19818134. Dr. Struck [1] appropriately points out the importance of infecting agents apart from bacteria in the burn-injured patient. Burn patients are frequently cited as having the highest risk for invasive ...

Background Burn is still a majordevastating condition in emergency medicine departments among both genders and all age groups in all developed and developing countries, leading to physical, psychological scars and economical burden. The present study aimed to determine the healing effect of topical treatment with Arnebia euchroma on second-degree burn wound in rats. Methods Fifty rats were ...

A surgical wound infection can develop at any time from two to three days after surgery until the wound has healed (usually 2 to 3 weeks post operation). Occasionally, an infection can occur several months after an operation (Humphreys, 2009; Anderson, 2011). Most surgical wound infections are limited to the skin, but can spread to deeper tissues as consequence of microbial invasion/infections,...

War wound infection and osteomyelitis caused by multidrug-resistant (MDR) Acinetobacter species have been prevalent during the 2003-2005 military operations in Iraq. Twenty-three soldiers wounded in Iraq and subsequently admitted to our facility from March 2003 to May 2004 had wound cultures positive for Acinetobacter calcoaceticus-baumannii complex. Eighteen had osteomyelitis, 2 burn infection...

Antimicrobial therapy remains to be the most important method of wound infection treatment. Systemically administered antimicrobials may not achieve therapeutic level in wound. On the other hand, in the absence of surgical debridement (due to any reason), most topically applied antimicrobials cannot penetrate the wound in therapeutic amount due to the presence of eschar. Burn eschar is a protei...

objectives: burn injury is one of the most health-threatening problems in the world. malva sylvestris (m. sylvestris) flowershave a high mucilage content and are used as a remedy for cut wound and dermal infected wounds in iranian folklore medicine. the purpose of this study was to investigate the effect of m. sylvestris cream on the second degree burn injury in rats. materials and methods: fiv...