A case of sporadic Burkitt lymphoma (sBL) presenting with jaw and lid involvement in a diabetic adult African American female and a review of adult orbital Burkitt lymphoma cases are presented. Lid edema, visual loss, ophthalmoparesis, proptosis, and sinusitis progressed over 4 weeks despite antibiotic and steroid treatment. Upper lid biopsy histopathological evaluation and immunophenotyping re...

The occurrence of Ewing sarcoma as a secondary malignancy is an extremely rare event in long-term cancer survivors. In addition, the occurrence of Ewing sarcoma in the adrenal gland is highly unusual. In this case report, we treated a 20-year-old male patient with cyclophosphamide, doxorubicin, vincristine, dexamethasone, and methotrexate and cytarabine chemotherapy following a diagnosis of Sta...

INTRODUCTION Burkitt-like lymphoma (BLL) is a provisional category of B-cell lymphoma which is morphologically intermediate between Burkitt lymphoma (BL) and large B-cell lymphoma (LBCL). The clinical significance of this morphology is controversial. PATIENTS AND METHODS We examined 41 cases of pediatric B-cell lymphoma by immunohistochemistry for proteins associated with proto-oncogenes c-my...

Burkitt lymphoma (BL) exhibits a characteristic immunophenotype that is positive for pan-B-cell antigens and CD10 and expresses clonal surface immunoglobulins (SIgs). We evaluated 35 BLs and identified atypical immunophenotypes in 4 including SIg light chain negativity in 4, negativity for B-cell antigens in 2, lack of CD10 in 1, and CD4 expression in 1. All 4 cases showed morphologic features ...

Mononucleosis? The recent announcement by the Doctors Henle of Philadelphia of the finding of an antibody against the EB virus in the sera of all cases of infectious mononucleosis ( TM ) studied’ was the source of some excitement in immunologic, oncologic, and hematologic circles. In a prime example of serendipity, the Henles, who were testing various sera for antibody to this newly-discovered ...

Mononucleosis? The recent announcement by the Doctors Henle of Philadelphia of the finding of an antibody against the EB virus in the sera of all cases of infectious mononucleosis ( TM ) studied’ was the source of some excitement in immunologic, oncologic, and hematologic circles. In a prime example of serendipity, the Henles, who were testing various sera for antibody to this newly-discovered ...