T HE EXCITATORY FUNCTION of GABA has been reported to contribute to the pathogenesis of some neuropsychological disorders, for example autism and epilepsy. The switch in GABA function, from inhibitory to excitatory, has been attributed to the alteration of cation-chloride cotransporters involved in the regulation of intercellular chloride concentration, chloride-intruder NKCC1 and chlorideextru...