conclusions regarding the findings of this study, it can be concluded that erα possibly cannot play an important role in the tumorigenesis and prognosis of the investigated malignant salivary gland tumors. results for acc, only one specimen expressed the er, and this was assessed as moderate. no specimens of mec expressed the er. the comparison of er expression between the two groups was not me...

BACKGROUND Critically ill patients who require mechanical ventilation are at risk for ventilator-associated pneumonia. Current data are conflicting as to the optimal diagnostic approach in patients who have suspected ventilator-associated pneumonia. METHODS In a multicenter trial, we randomly assigned immunocompetent adults who were receiving mechanical ventilation and who had suspected venti...

Bronchoalveolar lavage is widely used in the management of patients with interstitial lung diseases and is considered a safe procedure. We describe a patient who died with a picture consistent with acute pulmonary edema and septic shock following bronchoalveolar lavage. This potential complication has not been previously reported.

Dyskeratosis congenita (DC) is an unusual familial disorder primarily affecting the skin and its appendages. We report the case of a DC patient with chronic respiratory tract involvement, confirming the features previously reported by a small number of authors: 1) chronic bronchoalveolar involvement is not unusual in this disorder; 2) the main features are early sputum production with subsequen...

Activation of the adenosine A(2A) receptor has been postulated as a possible treatment for lung inflammatory diseases such as asthma and chronic obstructive pulmonary disease (COPD). In this report, we have studied the anti-inflammatory properties of the reference A(2A) agonist CGS-21680, given intranasally at doses of 10 and 100 microg/kg, in a variety of murine models of asthma and COPD. Afte...

background & objectives:  cd10 is a cell surface enzyme with metalloendopeptidase activity, also known as common acute lymphoblastic leukaemia antigen, which mainly serves as a marker for acute lymphoblastic leukemia (all). to date and to the best of our knowledge, only few comparative immunohistochemical studies have assessed cd10 expression in cutaneous epithelial neoplasms. our goal was ...

the coexistence of medullary thyroid carcinoma (mtc), papillary thyroid carcinoma (ptc) and parathyroid adenoma is an uncommon clinical entity. here, we report a case of mtc, ptc, and parathyroid adenoma diagnosed incidentally on a routine physical examination of the neck for the work-up of diabetes. the patient had neither symptoms of hypercalcemia nor those related to mtc and ptc.