It was proved by our experiments that on microwave irradiation, the mono- or bidentate phosphorus ligands generally applied in the palladium(II)-catalyzed P-C coupling reaction of aryl bromides and dialkyl phosphites or secondary phosphine oxides may be substituted by the excess of the >P(O)H reagent that exists under a tautomeric equilibrium. Taking into account that the reduction of the palla...

It is well known that the physical and chemical properties of ionic liquids (ILs) vary when the combination of cations and anions changes. It is thus possible to tune the properties of ILs on demand by choosing a suitable cation and anion combination. Consequently, ILs are commonly referred to as designer fluids. Many studies have demonstrated the usefulness of this strategy for controlling the...

Thermally induced [4+2] cycloaddition reactions of 5-ethanesulfonyl2-methylpyridazin-3(2H)-one (2) with pyrano[3,4-b]indol-3(9H)-ones (1, 4) affords isomeric pyridazino[4,5-b]carbazolones (3a,b, 5a,b), the product ratio depending on the substitution pattern of the diene. Two carbazolocarbazoles (6, 7) were obtained as side products. The antineoplastic activity of ellipticine (5,11-dimethyl-6H-p...

Open AccessCCS ChemistryRESEARCH ARTICLE1 Jun 2021Engineering Electronic Structure of Single-Atom Pd Site on Ti0.87O2 Nanosheet via Charge Transfer Enables C–Br Cleavage for Room-Temperature Suzuki Coupling Yangxin Jin†, Fei Lu†, Ding Yi†, Junmeng Li, Fengchu Zhang, Tian Sheng, Zhan, Ya’nan Duan, Gaochao Huang, Jinyang Dong, Bo Zhou, Xi Wang and Jiannian Yao Jin† Department Physics, School Scie...

In the present study, we studied the signal transduction mechanism that is involved in the expression of c-Jun protein evident after exposure of rat liver epithelial RL34 cells to the major end product of oxidized fatty acid metabolism, 4-hydroxy-2-nonenal (HNE). HNE treatment of the cells resulted in depletion of intracellular glutathione (GSH) and in the formation of proteinbound HNE in plasm...

Detection of the chemical constituents of hydrocarbons in the hydrocarbon-bearing fluid inclusions in diagenetic mineral cements, secondary fractures and overgrowths could be a useful indicator of the nature of oil in a basin. Microscopebased Raman spectroscopy is a non-destructive, optical vibrational spectroscopic technique that can precisely isolate and analyse hydrocarbon fluid inclusions (...

NEEDLEMAN, PHILIP, DELORES J. BLEHM, ANNE B. HARKEY, EUGENE M. JOHNSON. JR. AND STANLEY LANG : The metabolic pathway in the degradation of glyceryl trinitrate. J. Pharmacol. Exp. Ther. 179: 347-353, 1971. Glyceryl trinitrate (GTN) is degraded primarily in the liver by a partial denitration process catalyzed by organic nitrate reducta.se. The supporting evidence is as follows : 1) incubation of ...

Open AccessCCS ChemistryRESEARCH ARTICLE1 Apr 2021Spirobifluorene-Based Three-Dimensional Covalent Organic Frameworks with Rigid Topological Channels as Efficient Heterogeneous Catalyst Yamei Liu†, Chenyu Wu†, Qingzhu Sun, Fan Hu, Qingyan Pan, Jing Yinghua Jin, Zhibo Li, Wei Zhang and Yingjie Zhao Liu† College of Polymer Science Engineering, Qingdao University Technology, 266042 †Y. Liu C. Wu c...

•Highly reducing photocatalytic system•Inexpensive organocatalyst•Borylation of strong C–F, C–O, C–N, and C–S bonds•Various leaving groups >50 examples Cross-coupling reactions are essential tools in the modern synthesis drugs, natural products, materials. The recent developments radical generation have improved expanded classic metal-catalyzed cross-coupling even further. However, sp2 require ...

The rare-earth bis(alkyl) compound Sm{C(SiHMe2)3}2THF2 (1b) is prepared by the reaction of samarium(II) iodide and 2 equiv of KC(SiHMe2)3. This synthesis is similar to that of previously reported Yb{C(SiHMe2)3}2THF2 (1a), and compounds 1a,b are isostructural. Reactions of 1b and 1 or 2 equiv of B(C6F5)3 afford SmC(SiHMe2)3HB(C6F5)3THF2 (2b) or Sm{HB(C6F5)3}2THF2 (3b), respectively, and 1,3-disi...