In this paper, a new control chart to monitor multi-binomial processes is first proposed based on a transformation method. Then, the maximum likelihood estimators of change points designed for both step changes and linear-trend disturbances are derived. At the end, the performances of the proposed change-point estimators are evaluated and are compared using some Monte Carlo simulation experimen...

Why did you choose the profession of scientific investigation? Neither of my parents had anything to do with science. My father worked in a pawnshop, and my mother had a vocational high school diploma in sewing. I think my initial interest in science was pretty much instinctive: isn’t everyone curious as a child? This was reinforced by excellent science teachers in the New York City public scho...

OBJECTIVE To study the changes in body mass index (BMI) in a population-based cohort and their relationship with sociodemographic variables in a Mediterranean-country. METHOD A prospective population-based cohort with 8-year follow-up. The data used derive from the Cornellà-Health-Interview Survey Follow-up (CHIS.FU). 1008 people aged > or = 20 years (females=508; males=500) were interviewed ...

BACKGROUND Mixed effects logistic models have become a popular method for analyzing multicenter clinical trials with binomial data. However, the statistical properties of these models for testing homogeneity of odds ratios under various conditions, such as within-center and among-centers inequality, are still unknown and not yet compared with those of commonly used tests of homogeneity. METHO...

T here is, perhaps, no other class of neoplasm in the discipline of cutaneous medicine that evokes fear in patients as deeply as does melanoma. This sarcoma, seemingly unpredictable as it is in its clinical presentation and its histologic mimicry of melanocytic nevi and other lineages of neoplasms, is indeed worthy of our respectebut not our fear. Fear is overcome by knowledge, and methods of d...

Why did you choose the profession of scientific investigation? Neither of my parents had anything to do with science. My father worked in a pawnshop, and my mother had a vocational high school diploma in sewing. I think my initial interest in science was pretty much instinctive: isn’t everyone curious as a child? This was reinforced by excellent science teachers in the New York City public scho...

BACKGROUND Attendance rates of cervical screening programs can be increased by offering HPV self-sampling to non-attendees. Acceptability, DNA yield, lavage volumes and choice of hrHPV test can influence effectiveness of the self-sampling procedures and could therefore play a role in recruiting non-attendees. To increase user-friendliness, a frequently used lavage sampler was modified. In this ...

In order to control for confounding variables, epidemiologists often obtain data in the form of a 2 x 2 table. One variable is usually the disease status, while the other variable represents a dichotomous exposure variable that is suspected of being a risk factor. If a confounding variable is present, the data are often stratified into several 2 x 2 tables. The objectives of the analysis are to...

‎In this article‎, ‎we develop two nonparametric smoothing estimators for parameter of a time-variant parametric model‎. ‎This parameter can be from any parametric family or from any parametric or semi-parametric regression model‎. ‎Estimation is based on a two-step procedure‎, ‎in which we first get the raw estimate of the parameter at a set of disjoint time...