The aim of this study was to determine the relationship between parity and age at diagnosis, primary tumor size, axillary lymph node (ALN) metastasis, histological grade, and subtype classification in patients with breast cancer. Data from 392 patients with invasive breast cancer were collected and divided into four groups: nulliparous (parity 0), parity 1, parity 2, and parity ≥3. The relation...

BACKGROUND This study aimed to investigate the expression and significance of 5 types of miRNAs in breast cancer to provide a theoretical and practical foundation for using these miRNAs in the diagnosis and treatment of breast cancer, thereby improving medical services. MATERIAL/METHODS Stem-loop real-time RT-PCR was used to detect the expression levels of miR-145, miR-21, miR-10b, miR-125a, ...

The "round block" surgical technique in the treatment of a female patient with multiple, multicentric fibroadenomas in both breasts is presented. The advantages of this technique for patients with multicentric benign breast lesions are minimal postoperative scar and a favourable aesthetic result. Breast dimensions and the areolar diameter were measured in 203 subjects of Primorsko-Goranska coun...

OBJECTIVE We aimed to present our experience with rhomboid flap reconstruction, which is a simple technique, in breast cancer patients who underwent breast-conserving surgery. METHODS We reviewed the medical records of 13 patients with breast cancer who underwent rhomboid flap reconstruction. The patients were evaluated for tumor size, safe surgical margin, and other clinical and pathological...

This research is a model group, the probability that a patient is detected at any breast cancer or not breast cancer. Assessment of characteristics of abnormal growth of breast cancer cells such as Clump Thickness (X1), Uniformity of Cell Size (X2), Uniformity of Cell Shape (X3), Marginal Adhesion (X4), Single Epithelial Cell Size (X5), Bare Nuclei (X6), Bland Chromatin (X7), Normal Nucleoli (X...

PURPOSE Current AJCC/UICC staging of early breast cancer defines tumor stage using the largest focus, adding the suffix "(m)" to indicate multiplicity. This method may underestimate the total tumor burden in multifocal and multicentric breast cancer (MMBC). This study examines other measures of tumor size in MMBC to determine which provides the best fit in a multivariate model for survival outc...

The past few decades have seen an increase in both the role and the complexity of neoadjuvant therapy for breast cancer. Neoadjuvant therapy was initially described as systemic chemotherapy for inflammatory or locally advanced breast cancer but now entails a combination of chemotherapy, endocrine therapy, and targeted therapy. Neoadjuvant systemic therapy is employed for inoperable inflammatory...

BACKGROUND Liposuction has become a major therapeutic tool for body sculpting by dermatologic surgeons. To date, breast augmentation has been the only effective tool for breast enlargement. OBJECTIVE To review retrospectively records of patients who have undergone traditional tumescent liposuction to determine whether breast size is commonly affected by liposuction of other body areas. RESU...

background: because of the reported poor prognosis and absence of effective and specific therapeutic approaches, triple-negative breast cancer (tnbc) tumors have remained as an important area of investigations for clinicians and researchers. the aim of this study was to determine the clinical, pathological, histological, prognostic features, and outcome associated with this type of breast cance...

BACKGROUND It has long been known that both tumor size and the presence of malignant disease in the regional lymph nodes are indicators of outcome for patients with invasive breast carcinoma; however, the way in which these two characteristics could be integrated into an overall assessment of prognosis has not been obvious. METHODS Kaplan-Meier survival estimates (15 years) according to tumor...