PURPOSE The purpose of this study is to evaluate the use of second-look ultrasonography (US) for investigating additional suspicious lesions detected on preoperative staging magnetic resonance imaging (MRI) for breast cancer. METHODS Between September 2008 and August 2010, 1,970 breast MRIs were performed at our medical institution for the evaluation of breast cancer before surgery. Second-lo...

Background:Mammographic dense breast or high background parenchymal enhancement (BPE) in magnetic resonance imaging (MRI)hinders diagnostic accuracy for breast tumor detection. We retrospectively investigated relationship between BPE on MRI and mammographic densities along with the influential factors. Methods:Our study included 144 Japanese women who underwent both mammography and breast MRI u...

PURPOSE To evaluate whether the Breast Imaging Reporting and Data System (BI-RADS) MRI lexicon could reflect the genomic information of breast cancers and to suggest intuitive imaging features as biomarkers. METHODS Matched breast MRI data from The Cancer Imaging Archive and gene expression profile from The Cancer Genome Atlas of 70 invasive breast cancers were analyzed. Magnetic resonance im...

Introduction Breast MRI has been found to be extremely sensitive in the detection of invasive breast cancer, but false positive results has been problematic. The estimated sensitivity of gadoliniumenhanced breast MRI is usually cited as >95%. However, specificity values range from 37 – 97%. Furthermore, more than a decade after the introduction of breast MRI, there is still disagreement as to t...

MRI is an excellent option for detection of breast cancer for some selected groups, including those patients with a high probability to hit the disease. However, the high costs and low availability of the device have led to a decline in the application of imaging MRI. The aim of this study was to review usefulness of MRI as a new complementary way to detect breast cancer in routine annual check...

Breast cancer continues to be a significant public health problem in the world. Early detection is the key for improving breast cancer prognosis. In this way, magnetic resonance imaging (MRI) is emerging as a powerful tool for the detection of breast cancer. Breast MRI presently has two major challenges. First, its specificity is relatively poor, and it detects many false positives (FPs). Secon...

PURPOSE To compare MRI sequences for breast density measurements on a 3T MRI system using IDEAL (Iterative Decomposition of water and fat with Echo Asymmetry and Least squares estimation) as possible physiology-like reference. MATERIALS AND METHODS MRI examination was performed in 48 consecutive patients (mean age 41, years; range, 35-67 years) on a 3.0T scanner and 46 were included. All (fer...

Currently X-ray mammography is the most widely used method for early detection of breast cancer. However, the use of Dynamic Contrast Enhanced MRI (DCE-MRI) has gained wider attention, since it considerably improves tumor detection and classification by analyzing the flow of contrast agent within the breast tissue. In this paper we present MammoExplorer, a CAD application that combines advanced...

BACKGROUND While many studies have shown that hormones can influence background parenchymal enhancement (BPE) in breast magnetic resonance imaging (MRI), only few have directly address the effect of radiotherapy. The purpose of this study was to evaluate the impact of radiotherapy on BPE in breast MRI. MATERIALS AND METHODS A retrospective search identified 62 women with unilateral breast can...