objective: cd44+/cd24-/low breast cancer cells have tumour-initiating properties with stem cell-like features. breast cancer gene 1 (brca1) is a tumour suppressor gene that plays a crucial role in dna repair and maintenance of chromosome stability. the clinicopathological features of breast cancer in brca1 mutation carriers suggest that brca1 may function as a stem-cell regulator. materials and...

abstractepidermal inclusion cysts are uncommon in the breast, but the consequences can besevere when these cysts occur in the breast parenchyma. here, we report two suchcases. the patient in case 1 was an 37-year-old woman with a 3-cm palpable mass inthe right breast. mammography revealed a round and smoothly outlined mass, whichindicated a benign tumor, and sonography showed an irregularly sha...

Introduction: The extreme reduction in breast milk intake during the first days of life leads to weight loss, kidney failure and hypernatremia. The aim of this study was to examine the relationship between hypernatremia in neonates and way of maternal breastfeeding in hospitalized infants in Ghaem Hospital of Mashhad.   Materials and Methods: After obtaining parental consent, 687 infants referr...

Objective(s):Leptin receptor (LEPR) is a member of the class I cytokine receptor super-family that is known implicated in the initiation and progression of breast cancer. We have investigated the effect of Q223R polymorphism on the breast cancer susceptibly in a sample of Iranian subjects. Materials and Methods:We utilized a polymerase chain reaction (PCR) restriction fragment length polymorphi...

ever since psychological issues became a focus of attention in oncology, many studies have been conducted to quantitatively address the impaired sexual function among women diagnosed with breast cancer; however, we lack qualitative measurement of sexual dysfunction and patients’ needs. conducting research about “sexual function in breast cancer patients” in 2009 at the tehran cancer institute s...

background : breast cancer is a complicated disease and has various clinical manifestations and prognosis. the aim of this study is to make a breast cancer model suitable for basic, preclinical and clinical studies. materials and methods: five virgin bulb/c mice aged 6 weeks and spontaneous murine mammary adenocarcinoma cells (mmac) were used. after anesthesia induction, 1-3 million of mmacs we...

alloderm® (lifecell corp.; brancburg, nj) is an acellular dermal matrix (adm) that serves as an immunologically inert scaffold in plastic surgery. in breast reconstruction, it is used as a filler for lumpectomy defects and can be used to create the inferolateral portion of the tissue expander pocket or implant pocket in postmastectomy patients. however, there are limited reports of the radiolog...

background: emotional intelligence (eq) is positively associated with mental health and it can have a crucial role in mental disorder therapy by suitable coping mechanisms. the present study aimed to evaluate the relationship of eq with anxiety and depression among the women with breast cancer. subjects and methods: during 2013 and in a cross-sectional study, 98 breast cancer patients (14 to 21...

recent studies have indicated the profound  anti-tumor activity of artemisinin's compounds,  among  which;  arteether  is an  oil-soluble derivative of  artemisinin with an endoperoxide bridge that can induce apoptosis in tumor cells but not in the normal cells. an experiment was carried out on tumor-bearing balb/c mice to estimate the effects of arteether  on  tumor  growth  and  antitumor  im...

treatment related acute myeloid leukemia (t-aml) is well documented phenomenon after chemotherapy. in this subgroup of patients acute promyelocytic leukemia (apml) due to delayed complication of using anthracycline is very rare occurrence. very few cases are reported in world literature. we are reporting a rare case of occurrence of t-apml in cured breast cancer patient treated with doxorubicin...