nature nanotechnology | VOL 2 | MAY 2007 | www.nature.com/naturenanotechnology 273 MSNs and the green fl uorescent protein (GFP) marker encoded in the DNA was expressed in the cells and detected by microscopy. Delivery is effi cient because the minimum amount of DNA required to detect marker expression was 1,000-fold lower than that required when using conventional methods to deliver DNA into p...

due to the high incidence of deaths from breast cancer, high cost of treatment and limited resources, the need to formulate and implement effective programs in reducing the burden of disease is obvious. care, control and creation of cancer information system having an infrastructure from collection of minimum data sets (mds) are the top priorities of research in iran's ministry of health.this i...

objectives: ziziphus jujube (jujube) plant has exhibited numerous medicinal and pharmacological properties including antioxidant and anti-inflammatory effects. this study was carried out to investigate its anti-cancer and pro-apoptotic abilities in human cervical and breast cancer cells in vitro. materials and methods: the cervical ov2008 and breast mcf-7 cancer cells were incubated with differ...

Breast cancer is the deadliest form of in women, but it also has very high survival rates when treated early. Existing breast detection methods such as mammography are ineffective early due to low uptake among women and need for regular screening. Therefore, biosensors have been proposed an alternative method cost-effective screening which may encourage more go regularly. In this paper, a gold ...

We describe a new method for the detection of miRNA in biological samples. This technology is based on the isothermal nicking enzyme amplification reaction and subsequent hybridization of the amplification product with gold nanoparticles and magnetic microparticles (barcode system) to achieve naked-eye colorimetric detection. This platform was used to detect a specific miRNA (miRNA-10b) associa...

The molecular scenario of breast cancer has become more complex in the last few years. Distinguishing between BRCA-associated, sporadic, HER2-enriched and triple-negative tumors is not sufficient to allow effective clinical management. Basal-like breast cancer, a subtype of triple-negative breast cancer, differs from others grouped under this heading. Commonalities between BRCA-related tumors a...

Herceptin, the monoclonal antibody, was successfully immobilized on gold nanoparticles (GNPs) to improve their precise interactions with breast cancer cells (SK-BR3). The mean size of the GNPs (29 nm), as determined by dynamic light scattering, enlarged to 82 nm after herceptin immobilization. The in vitro cell culture experiment indicated that human skin cells (FB) proliferated well in the pre...

the evaluate the diagnostic value of image guided fine needle aspiration (fna) in breast lesions, the cytologic results of 401 patients were studied. all patients had either unpalpable masses or lesions who were hardly possible to localize by palpation and fna was performed by single radiologist under ultrasound guide in all cases. the cytologic results were divided into four categories (inconc...

background: in some verses in holy quran; 233 surat al-baghare , 15 al-ahghaf , 14 loghman and 6 al-talagh, breastfeeding, gravidity, and parity recommended to the parents and expected their children to be accountable to the parents; particularly to mothers due to tolerate of pregnancy and breastfeeding duration. methods: the case-control study included 376 patients diagnosed between      2001-...