DNA damage by ultraviolet (UV) light poses a risk for mutagenesis and a potential hindrance for cell cycle progression. Cells cope with UV-induced DNA damage through two general strategies to repair the damaged nucleotides and to promote cell cycle progression in the presence of UV-damaged DNA. Defining the genetic pathways and understanding how they function together to enable effective tolera...

Data-driven approaches are envisioned to build future Edge-IoT systems that satisfy IoT devices demands for edge resources. However, significant challenges and technical barriers exist which complicate resource management of such systems. can demonstrate a wide range behaviors in the demand extremely difficult manage. In addition, resources fairly efficiently by setting is challenging task. thi...

Blueberry replant disease (BRD) is an emerging threat to continued blueberry (Vaccinium spp.) production in Georgia and North Carolina. Since high populations of ring nematode Mesocriconema ornatum were found to be associated with commercially grown blueberries in Georgia, we hypothesized that M. ornatum may be responsible for predisposing blueberry to BRD. We therefore tested the pathogenicity...

Dairy calves are vulnerable to infectious diseases, particularly diarrhoea and bovine respiratory disease (BRD), causing mortality and reducing welfare and growth. A prospective cohort study was performed on 11 UK dairy farms to determine the underlying causes for calf disease. This first paper describes the incidence, timing and duration of infectious disease, mortality rates, passive transfer...

ABSTRACT Background Bovine respiratory disease (BRD) is the most common disease in the beef industry, and diagnosis based on visual observation of clinical signs is challenging. Cattle may alter behavior when diseased and technology exists to remotely monitor these behavioral changes. The objective of this study was a preliminary assessment of the ability of a remote early disease identificatio...

1 Department of Computer Science, Dartmouth College, Hanover, NH 03755, USA 2 Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA 3 Department of Chemistry, Dartmouth College, Hanover, NH 03755, USA 4 Department of Biological Sciences, Dartmouth College, Hanover, NH 03755, USA 5 Corresponding authors. 6211 Sudikoff Laboratory, Hanover, NH...

A direct Giemsa technique is described for the selective staining of Brd-U-substituted chromatin. It can advantageously be used for sister-chromatid exchange analysis and for the detailed cytological study of the mouse kinetochores. Presumptive inversions within the centromeric region of chromosomes 4 and 18 in the C57Black/6J mouse are described.