Background: Tuberous sclerosis complex (TSC) is a genetic disorder characterized by the development of benign tumors in multiple organs and tissues, especially brain, kidneys, heart, lungs, skin. Brain lesions are frequently associated with cognitive deficits, neuropsychiatric disorders, learning disabilities, seizures. Seizures occur approximately 80% patients 30% to 60% them had West Syndrome...

Neurodegenerative disorders, ischemic brain diseases, and tumors are debilitating diseases that severely impact a person's life could possibly lead to their demise if left untreated.