Lesions in the cerebellar vermis abolish acquisition of fear-conditioned bradycardia in animals and human patients. The δ2 glutamate receptor (GluD2) is predominantly expressed in cerebellar Purkinje cells. The mouse mutant ho15J carries a spontaneous mutation in GluD2 and these mice show a primary deficiency in parallel fiber-Purkinje cell synapses, multiple innervations of Purkinje cells by c...

Healthy teens and adults performed four vagotonic maneuvers. A large series of strabismus surgery patients had deliberately quantified tension on extraocular rectus muscles during general anesthesia. The mean bradycardia was greatest for diving response (apneic facial exposure to cold) and Valsalva maneuver and least for pressure on the globe and carotid sinus massage. Bradycardia occurred for ...

The purpose of this study was to investigate the feasibility of different fetal heart rate (FHR) ranges in the nonstress test (NST) and to better understand the meaning of mild bradycardia and/or tachycardia without non-reassuring patterns. We employed the heredity to show that mild bradycardia (100-119 beats per minute, bpm) and mild tachycardia (161-180 bpm) regressed to the normal FHR range ...

background  apnea is one of the most common problems in preterm neonates. this study aimed to evaluate the effectiveness of aromatherapy on the reduction of apnea, bradycardia, and pulse oximetry (spo2) in premature infants. materials and methods in a clinical trial study, 60 preterm neonates randomly divided in two groups and exposed to aromatherapy with rosa damascenes distillate or distilled...

A 6-year-old, 3.0 kg, neutered female, Yorkshire terrier was referred for orthopedic surgery. Cardiac arrest followed unsuccessful treatment of bradycardia and systemic arterial hypotension under general anesthesia. Postmortem examination revealed hypertrophic cardiomyopathy. A possible relationship between treatment of bradycardia, systemic arterial hypotension, and sudden cardiac death is des...

Purpose: The aim of this study is to provide data about diagnosis, treatment, and results the patients poisoned by drugs affecting cardiovascular system. 
 Materials Methods: Patients aged 18 over who applied emergency department with drug poisoning cardiovasculer system were included in study. demographic data, doses, treatment time development shock or bradycardia, antidotes invasive pro...

A 58-year-old man without comorbidity presented with high fever, chills, and myalgia. Examination showed right inguinal lymphadenopathy; an eschar was present in the ankle region (Figure 1). His blood pressure was 100/60 mmHg, heart rate was 70 beats/minute, and the electrocardiogram (ECG) showed normal sinus rhythm (Figure 2A). The platelet count was 74,000/μL, total bilirubin was 1.3 mg/dL, a...

We reported previously that the nitric oxide synthesis inhibitor N(omega)-nitro-L-arginine methyl ester (L-NAME) decreases cardiac output. Several studies have shown that inhibition of nitric oxide synthesis decreases the heart rate. In the present study, we investigated the effect of a single bolus administration of L-NAME on blood pressure and heart rate monitored for one hour in anesthetized...

Acute increases in peripheral osmolality evoke a pressor response and baroreflex-mediated bradycardia. These experiments were designed to determine if the fall in heart rate during peripheral sodium loading is 1) equivalent to bradycardia accompanying phenylephrine (PE) infusion, 2) mediated by the parasympathetic (PSNS) or sympathetic (SNS) nervous system, and 3) controlled by the median preop...

Apnea is nearly universal among very low birth weight (VLBW) infants, and the associated bradycardia and desaturation may have detrimental consequences. We describe here very long (>60 s) central apnea events (VLAs) with bradycardia and desaturation, discovered using a computerized detection system applied to our database of over 100 infant years of electronic signals. Eighty-six VLAs occurred ...