Multivalent interaction between boronic acids immobilized on quartz crystal microbalance (QCM) sensor surface and the carbohydrates modified Au-nanoparticle (AuNP) has been demonstrated for the development of a sensitive carbohydrate biosensor. Briefly, a boronic acid-containing polymer (boropolymer) as multivalent carbohydrate receptor was oriented immobilized on the cysteamine coated electrod...

A modified procedure for the synthesis of polychlorinated biphenyls (PCBs) utilizing the Suzuki-coupling, a palladium-catalyzed cross-coupling reaction, is described. The coupling of (chlorinated) benzene boronic acids with bromochlorobenzenes, using Pd(dppf)(2)Cl(2) (dppf = 1,1'-bis(diphenylphosphino)ferrocene) as the catalyst and aqueous sodium carbonate as the base, gave the desired PCB cong...

Boronic acids have been illustrious in the literature back in 1860 [1], developing over the years into a wide studied area of chemistry. After the approval of Velcade® as proteasome inhibitor, boronic acids have emerged as a unique lead for several malignant tumors, as β-lactamase inhibitors, NS3 protease inhibitors, amino-acyl tRNA synthase inhibitors, and anticoagulants. Boronic acids and its...

During continuing studies with a novel oxidative gold oxyarylation reaction, arylsilanes were found to be competent coupling partners, providing further evidence for an intramolecular electrophilic aromatic substitution mechanism. While providing yields complementary to those of the previously described boronic acid methods, the use of trimethylsilanes reduces the observation of homocoupling by...

A procedure-dependent selective construction of two isomers of trimeric boronic esters was realized. A capsule-like trimeric boronic ester was constructed by the direct connection of two kinds of self-assembled boronic esters via [3+2] cycloaddition, while the tricyclic trimeric boronic ester was obtained by the self-assembly of pre-connected components.

The results of a solid-state (11)B NMR study of a series of 10 boronic acids and boronic esters with aromatic substituents are reported. Boron-11 electric field gradient (EFG) and chemical shift (CS) tensors obtained from analyses of spectra acquired in magnetic fields of 9.4 and 21.1 T are demonstrated to be useful for gaining insight into the molecular and electronic structure about the boron...