Body Solar system bodies are observed at many scattering angles. The reflection and polarization change withphase angle of light scattered from particulates has been studied for a century in the lab in efforts tounderstand clouds, aerosols, planetary ring systems and planetary regoliths. These effects must beunderstood in order to infer surface properties from astronomical data. The...

•MP31 is a micropeptide encoded from 5? UTR of PTEN•MP31 localizes in mitochondria and limits lactate-pyruvate conversion•MP31 loss promotes lactate metabolism OXPHOS glioblastoma•Recombinant MP31 has therapeutic effects on GBM mice model without inducing toxicity The metabolic role micropeptides generated untranslated regions remains unclear. Here we describe MP31, by the upstream open reading...

The problem of computing with temporal information was early recognised within the area of arti cial intelligence, most notably the temporal interval algebra by Allen has become a widely used formalism for representing and computing with qualitative knowledge about relations between temporal intervals. However, the computational properties of the algebra and related formalisms are known to be b...

One of the most important decisions a president will make after an election is what kind relationship he/she have with cabinet secretaries and agency heads. Will be controlling or autonomy giving? George H. W. Bush created contractor presidency, one that subcontracted management to officials, giving them considerable freedom, making policy entrepreneurs. Yet, when it came time support initiativ...

Human biomonitoring using the micronucleus (MN) assay on exfoliated buccal cells is an invasive approach for the assessment of genetic damage in exposed populations. To determine the genotoxic effects of spray painters, MN assay was carried out in exfoliated buccal epithelial cells of 94 spray painters and 80 controls. From each individual, 2,000 exfoliated buccal cells were analyzed. The indiv...

With a new "civilization killer" strain of the AIDS virus emerging, it has become critical fordefense forces to take a primary role in preventing the spread of the contagion and in preserving thestructures and strengths of societies in developing states. As well, the virulent spread of the new strains ofthe disease will impose significant constraints on international force projectio...

Optical imaging methods have revealed the spatial arrangement of orientation columns across striate cortex, usually summarized in terms of two measurements at each cortical location: (i) a \best" stimulus orientation, corresponding to the stimulus orientation that elicits a maximal response , and (ii), the magnitude of the response to the best orientation. This mapping has been described as con...

Objective. To evaluate the safety and efficacy of abatacept plus methotrexate (MTX) over 5 years in patients with rheumatoid arthritis. Methods. Patients were randomized to abatacept 10 or 2 mg/kg or placebo, plus MTX. Patients completing the 1-year, double-blind period entered the longterm extension, where all patients received a fixed dose of abatacept ~10 mg/kg. We describe safety analyses f...

Peptidoglycan hydrolases are key enzymes in bacterial cell wall homeostasis. Understanding the substrate specificity and biochemical activity of peptidoglycan hydrolases in Mycobacterium tuberculosis is of special interest as it can aid in the development of new cell wall targeting therapeutics. In this study, we report biochemical and structural characterization of the mycobacterial Nacetylmur...

The search for an all-purpose luting system for final cementation that fulfills the properties necessary for definitive placement of cast metal, porcelain-metal, resin, and all-ceramic fullcoverage restorations has been limited by the physical properties of the cements that have been available. Currently the clinician has many choices for cementation. Despite the challenges of the current resto...