BACKGROUND The World Health Organization classification of myeloproliferative neoplasms discriminates between essential thrombocythemia and the prefibrotic phase of primary myelofibrosis. This discrimination is clinically relevant because essential thrombocythemia is associated with a favorable prognosis whereas patients with primary myelofibrosis have a higher risk of progression to myelofibro...

which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. A 60-year-old man presented with fever for 2 weeks. Ultrasonography and contrast-enhanced abdominal computed tomography revealed retroperitoneal and mesenteric lymphadenopathy. Fine-needle aspiration cytology of a right inguinal lymph node showed a monotonou...

BACKGROUND: Malignant neoplasms with lesions of the chest are quite rare in sternum and range from 0.5 to 3.1% total number patients bone tumors all localizations. In this connection, there few publications describing tactics surgical treatment methods prosthetics formed defect. The present article describes a clinical case successful application an individual prosthesis manubrium G1 chondrosar...

Background: Primary malignant bone tumors are heterogeneous groups of neoplasms, which affect mainly children and adolescents. The most common types are Osteosarcoma, Ewing sarcoma and chondrosarcoma. Elevation of sCD30 and sCD40L has been observed in lymphoma, leukemia and autoimmune disorders. Objective: To evaluate serum concentrations of sCD30 and sCD40L in patients with primary malignant b...

Introduction. Pneumocephalus is a clinical entity characterised by the presence of gas in intracranial space. It can result from many different causes. The most common cause head or facial trauma. Other causes include neoplasms, infections, and surgical diagnostic procedures. Spontaneous non-traumatic pneumocephalus rare condition caused bone defects, malformations, tumours, intravenous air inj...

Background & objective:Primary pleural neoplasms are rare entities compared with the pleural involvement by metastatic carcinoma. The current study aimed at investigating the complete spectrum of pleural neoplasms and differentiating between them with the aid of immunohistochemistry (IHC). Methods: Consecutive pleu...

Abstract A newly described entity called “calcified chondroid mesenchymal neoplasms” includes neoplasms with variable amounts of calcification and FN1 fusions [Liu et al, Mod Pathol 2021]. We report a case left temporal bone giant cell granuloma-like lesion that also shows an FN1-TEK fusion. Close monitoring MRI images after surgery has showed no recurrence. Case report: 33-year-old male develo...

Malignant hypercalcemia is defined as the presence of high serum calcium concentrations in context tumor pathology. It most common cause hospitalized patients with solid tumors or hematological neoplasms where postulated mechanisms are bone metastases and / secretion factors that activate resorption by cells. can be detected a finding study asymptomatic associated severe clinical manifestations...

A synchronous diagnosis of a plasma cell neoplasm (PCN) and non-plasma hematologic malignancy is very rare. We report what we believe the first instance PCN B lymphoblastic leukemia/lymphoma (B-ALL) diagnosed at initial presentation. The patient underwent laboratory evaluation for an underlying neoplasm, including immunology studies, bone marrow biopsy, flow cytometry immunophenotyping. Serum l...

Primary cutaneous neoplasms of myoepithelial differentiation are uncommon. Cutaneous myoepithelial carcinomas are rare. We report a case of cutaneous myoepithelial carcinoma in a 47-year-old man with a history of end-stage renal disease and renal transplant 19 years prior who presented to the hospital with a 3-month history of diffuse bone pain and an ulcerated scalp mass with multiple satellit...