The purpose of this study was to explore the effectiveness combined one-stage reconstruction extensive complex defects lower limb tissues and analyze postoperative complications. Material methods . research involved 25 patients with bone soft tissue extremities. first group included 16 patients, where replacement soft-tissue leg carried out one bone-skin graft. second consisted 9 who, along maj...

BACKGROUND Osteoinductive bone substitutes are defined by their ability to induce new bone formation even at heterotopic implantation sites. The present study was designed to analyze the potential osteoinductivity of two different bone substitute materials in caprine muscle tissue. MATERIALS AND METHODS One gram each of either a porous beta-tricalcium phosphate (β-TCP) or an hydroxyapatite/si...

BACKGROUND Although bone specimens were established 25 years ago as the gold standard for etiologic diagnosis of chronic osteomyelitis, recent studies suggest that nonbone specimens are as accurate as bone to identify the causative agent. We examined concordance rates between cultures from nonbone and bone specimens in 100 patients. METHODS Prospective study conducted at Hospital Universitari...

in a novel dual bed reactor fischer-tropsch synthesis was studied by using two diffrent cobalt catalysts. an alkali-promoted cobalt catalyst was used in the first bed of a fixed-bed reactor followed by a rutenuim promoted cobalt catalyst in the second bed. the activity, product selectivity and accelerated deactivation of the system were assessed and compared with a conventional single bed react...

AIM Evaluate the diagnostic accuracy of 68Ga-labeled HBED-CC-PSMA-PET/MRI for detection of recurrent PCa in comparison to PET/CT. METHODS 48 patients with suspected recurrent PCa underwent PET/CT after injection of the 68Ga-HBED-CC-PSMA ligand followed by integrated PET/MRI. Image analysis was performed by nuclear medicine physicians and radiologists with respect to the detection of lymph nod...

The present study investigated the influence of granule size of 2 biphasic bone substitutes (BoneCeramic® 400-700 μm and 500-1000 μm) on the induction of multinucleated giant cells (MNGCs) and implant bed vascularization in a subcutaneous implantation model in rats. Furthermore, degradation mechanisms and particle phagocytosis of both materials were examined by transmission electron microscopy ...

Prolonged microgravity exposure disrupts bone, muscle, and cardiovascular homeostasis, sensory-motor coordination, immune function, and behavioral performance. Bone loss, in particular, remains a serious impediment to the success of exploration-class missions by increasing the risks of bone fracture and renal stone formation for crew members. Current countermeasures, consisting primarily of res...

Introductions Tissue-engineered bone regeneration requires not only a cell population capable of creating new bone and a biocompatible scaffold, but also the formation of an appropriate vascular bed to support the metabolic needs of bone tissue. Slow ingrowth of blood vessels can lead to cell loss through hypoxic cell death during the early post-implantation stage. To overcome the obstacle of n...

BACKGROUND AND PURPOSE Healing of acetabular bone grafts may be difficult to assess in conventional radiographs. We used PET to analyze healing of morselized bone allografts, impacted in large osteolytic acetabular defects at revision arthroplasty. PATIENTS AND METHODS 7 cases had a cup revision because of loosening, with repair of a segmental defect using a perforated, wide and thin plate. T...

Reporting two cases one of centimetres breadth and the other four exposed tibia bone devoid periosteum due to post debridement involving elevator remove infective tissue which was successfully covered by a simple procedure with MatriDerm® split skin graft in single stage. Tibia not drilled sprout granulation from marrow create granulated vascularised bed for second-stage grafting. It avoided lo...