Cyclins play a fundamental role in the cell cycle. Recent studies have focused on their role in the development of various malignancies. The objective of this study was to evaluate and compare the expression of cyclins A and E in common nevi, dysplastic nevi and malignant melanomas, and to investigate the relationship between cyclin expression and some pathological parameters such as tumor thic...

Because nevi share risk factors with melanoma and are strong risk factors for melanoma, they are suitable biomarkers for evaluating sun protection programs. Kidskin was a trial of a school-based sun protection program in Western Australia that included high and moderate intervention groups and a control group. Schools were assigned nonrandomly to groups. The primary outcome was number of nevi o...

Large congenital melanocytic nevi are cutaneous lesions regarded by many as premalignant; estimates of malignancy incidence range from 0 to 42 percent. Given the often complex and extensive nature of large congenital melanocytic nevi resection and reconstruction, the risk of malignant transformation is a crucial factor that surgeons and families must weigh when deciding whether or not to excise...

Because nevi share risk factors with melanoma and are strong risk factors for melanoma, they are suitable biomarkers for evaluating sun protection programs. Kidskin was a trial of a school-based sun protection program in Western Australia that included high and moderate intervention groups and a control group. Schools were assigned nonrandomly to groups. The primary outcome was number of nevi o...

M elanocytic nevi, commonly referred to as moles, are very common in children, and the overwhelming majority of melanocytic nevi in children are benign. Given the increased general awareness of melanoma, however, caregivers often express concerns about the development or appearance of their child’s moles. An understanding of the more common types of melanocytic nevi seen in children and of the ...

Monitoring of atypical nevi is an important step in early detection of melanoma, a clinical imperative in preventing the disease progression. Current standard diagnosis is based on biopsy and histopathological examination, a method that is invasive and highly dependent upon the physician’s experience. In this work, we employed a clinical multiphoton microscope to image in vivo and non-invasivel...

Citation: Scope A. Dermatoscopy and Skin Imaging: The section to share your morphological observations and scientific insights. It is a great pleasure and honor to be the Editor of the Der-matoscopy and Skin Imaging Section in Dermatology Practical and Conceptual. We live in very exciting times in clinical dermatology. The use of primary morphology in diagnosis is natural for dermatologists and...

study in Japan. Arch Dermatol. 2004;140(10):1233-1238. 6. Altamura D, Zalaudek I, Sera F, et al. Dermoscopic changes in acral melanocytic nevi during digital follow-up. Arch Dermatol. 2007;143(11):13721376. 7. Ozdemir F, Karaarslan IK, Akalin T. Variations in the dermoscopic features of acquired acral melanocytic nevi. Arch Dermatol. 2007;143(11):13781384. 8. Minagawa A, Koga H, Saida T. Dermos...

Alias: Familial atypical mole-malignant melanoma syndrome (FAMMM); B-K mole syndrome Inheritance: Autosomal dominant with high penetrance and variable expressivity; the frequency of DNS is difficult to evaluate because a number of cases without malignant evolution are not recorded; DNS defines patients with numerous dysplastic nevi. FAMMM defines families where coexist numerous nevi with malign...

An eccrine nevus is a rare hamartoma characterized by an increase in the number or size of eccrine glands. Eccrine nevi usually present as localized hyperhidrosis and are not associated with overlying skin abnormalities. However, among the cases that have been reported in the literature, some unique presentations of eccrine nevi have been demonstrated, including a pigmented patch, a depressed n...