Metabolites present in human blood document individual physiological states influenced by genetic, epigenetic, and lifestyle factors. Using high-resolution liquid chromatography-mass spectrometry (LC-MS), we performed nontargeted, quantitative metabolomics analysis in blood of 15 young (29 ± 4 y of age) and 15 elderly (81 ± 7 y of age) individuals. Coefficients of variation (CV = SD/mean) were ...

objective: a research was carried out to investigate the effects of nettle (urtica dioica) powder (np) and essential oil (ne) on performance, blood metabolites, carcass characteristics and antioxidant stability in broiler chicks. methods: the treatments were t1: control diet, t2: control diet + 5g/kg np, t3: control diet + 10 g/kg np, t4: control diet + 5g/kg ne and t5: control diet + 10 g/kg n...

Along with the known risk factors of cardiovascular diseases (CVDs) constituting metabolic syndrome (MS), gut microbiome and some its metabolites, in particular trimethylamine-N-oxide (TMAO), are actively discussed. A prolonged stay under natural hypoxic conditions significantly multi-directionally changes ratio strains their metabolites feces blood, which is basis for using hypoxia preconditio...

Background: Artificial insemination with chilled sperm is a reproductive biotechnology often used in horse breeding. However, maintaining the acceptable quality after cooling, which affects frequency of pregnancy, remains an urgent problem at present time. Therefore, clarifying role important physiological metabolites, such as L-carnitine and nitric oxide, significant aspect terms possible impr...

keyvan karkoodi*, saeed khalajzadeh department of animal science, saveh branch, islamic azad university, saveh, iran   *corresponding author's e-mail: [email protected]   received: 12 august 2013 accepted: 21 november 2013   abstract   thirty neonatal male holstein calves fed by starter diets containing ground wheat (gw) or dry-rolled wheat (drw) to 12 weeks of age. skeletal growth ...

The influence of dietary oxidized oil was studied on laying hen performance, egg quality and blood metabolites.  Experiment was conducted on 160 laying hens (Hy-Line W-36, 54-61 wk of age) in a completely randomized design with five treatments and four replicated cages containing eight birds per cage. Dietary treatments replaced fresh soybean oil in the control diet (3% fresh soybean oil, 15.25...

objective(s): the object of the study is to examine the effects of δ9-tetrahydrocannabinol (thc) against oxidative stress in the blood and excretion of thc metabolites in urine of type 2 diabetic rats. materials and methods: the control (n=8), thc control (n=6), diabetes (n=8) and diabetes + thc (n=7) groups were created. type 2 diabetes was induced by nicotinamide (na, 85 mg/kg) + streptozotoc...

A metabolomics approach for prediction of bacteremic sepsis in patients in the emergency room (ER) was investigated. In a prospective study, whole blood samples from 65 patients with bacteremic sepsis and 49 ER controls were compared. The blood samples were analyzed using gas chromatography coupled to time-of-flight mass spectrometry. Multivariate and logistic regression modeling using metaboli...