Multidisciplinary research from the last few decades has revealed that Factor XIII subunit A (FXIII-A) is not only involved in blood coagulation, but may have roles various diseases. Here, we aim to summarize data studies involving patients with mutations F13A1 gene, performed FXIII-A knock-out mice models, clinical and histological assessing correlations between diseases severity levels, as we...

Brain-targeted drug delivery is a field of research that seeks to develop new methods for delivering drugs the brain. This done by overcoming blood-brain barrier (BBB), network cells tightly regulate flow substances between blood and Most time lipophilic are easily cross brain but few them less soluble in lipid therefore they don’t barrier. After review we concluded can improve solubility using...

the identification of early markers of atopy in cord blood of newborns at delivery may offer prediction of future allergic sensitization. the aim of this study was to evaluate the relationship between cord blood interleukin-13 (il-13) and interferon-gamma (ifn-γ) and development of allergic diseases during the first five years of life. umbilical cord blood samples were collected at the time of ...

many investigations have proved relations between abo blood groups with some diseases and factor viii and von willebrand level in plasma. in this study we investigated a relation between abo blood groups and factor viii and ix inhibitors in 102 patients with haemophilia a and 48 patients with haemophilia b. the assay of inhibitor was done by bethesda method. there were no relation between abo b...