نتایج جستجو برای: blood coagulation factors
تعداد نتایج: 1686867 فیلتر نتایج به سال:
Editor: STANFORD WEssLu, M.D.
Referate – Abstracts – Analyses Physiology and Pathology of Blood Coagulation A Review of the Literature of 1950* (First Part) F. ROLLER, Zurich 1. General aspects. – 2. Prothrombin. – 3. Factor V (ac-globulin, labile factor). – 4. Thromboplastin. – 5. Platelets. – 6. Thrombín, antithrombin. – 7. Fibrinogen, fibrin. – 8. Heparin. – 9. Other anticoagulants. – 10. Thrombosis. -11. Hemophilia. 1. ...
By LEANDRO M. TOCANTINS, M.D. T ENTATIVE explanations of the mechanism of coagulation of the blood must necessarily be concerned as well with the equally important problem of the maintenance of its fluidity in the circulation. Fluidity and coagulability are properties of the blood that are in a sense antagonistic to each other. To understand what promotes coagulation, one must also be familiar ...
Studies of the prothrombin time (PT) have revealed that contact with borosilicate or commercial siliconized borosilicate markedly shortens the PT. This shortening is related to the activation of the contact phase of blood coagulation. This shortening of the PT occurs in both normal whole blood and plasma when stored in borosilicate or siliconized borosilicate tubes at 4 degree C and to a lesser...
The process of fibrin clot formation is a series of complex and well-regulated reactions involving blood vessels, platelets, procoagulant plasma proteins, natural inhibitors, and fibrinolytic enzymes. Vasculitis can be caused by a variety of different agents as bacteria, viruses, protozoal, rickettsial organisms, toxic, drugs, medications, and neoplasms. The most common cause of vasculitis is t...
THERE are so many factors concerned in the coagulation of blood that intermediate reactions between them are inevitable. According to the classic theory, thromboplastin, a lipoprotein or lipid released by injury to cells or platelets, initiates the coagulation of blood. There is evidence (Flynn and Coon, Mann and Hum) that before it reacts with prothrombin, thromboplastin reacts with at least t...
Nafamostat mesilate (FUT-175) is a protease inhibitor, working as an inactivator of coagulation, fibrinolysis and platelet aggregation. Although FUT-175 directly blocks contact factors in coagulation, it also may decrease activation of humoral cascade systems when used in cardiopulmonary bypass circuits. We performed an in vitro study using fresh human blood in the following cardiopulmonary byp...
Among the abounding lessons we learned from SARS-C0V-2 pandemic is uttermost determinant that people are not equal before severity of COVID-19. Indeed, disease course differs with age, gender, ethnicity, underlying clinical conditions and virus variants. Other diseases modifying factors associated genetic traits such as those driving immune response, blood groups, coagulation system ACE2 recept...
We evaluated systemic alterations to the blood coagulation system that occur during a coronary thrombotic event. Peripheral blood coagulation in patients with acute coronary thrombosis was compared with that in people with stable coronary artery disease (CAD). Blood coagulation and platelet activation at the microvascular injury site were assessed using immunochemistry in 28 nonanticoagulated p...
Prothrombin complex concentrates (PCCs) are widely administered for emergency oral anticoagulation reversal and for coagulation defects in liver disease. Pharmacokinetic data may help to optimize treatment. The objective of this study was to characterize the pharmacokinetics of a PCC (Beriplex P/N) containing coagulation factors II (FII), VII (FVII), IX (FIX) and X (FX) and anticoagulant protei...
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