The place of surgery in the management of patients with bleeding into the stomach or duodenum is largely governed by two aspects of the haemorrhage: the total volume of blood lost and the rate of bleeding. Other factors which are of importance are the cause of the bleeding and the age of the patient. Severe bleeding is one of the most demanding emergencies, and the decision may need to be made ...

OBJECTIVE Inequalities in health are well recognized in cardiovascular disease and cancer, but in comparison, we have minimal understanding for upper gastrointestinal bleeding. Since furthering our understanding of such inequality signposts preventable disease, we investigated in detail the association between upper gastrointestinal bleeding and socioeconomic status. DESIGN Population-based c...

BACKGROUND The tonsillectomy is one of the most frequently performed surgical procedures. Given the comparatively frequent postsurgical bleeding associated with this procedure, particular attention has been paid to reduction of the postoperative bleeding rate. In 2006, we introduced routine suturing of the faucial pillars at our clinic to reduce postoperative haemorrhage. METHODS Two groups f...

BACKGROUND AND AIMS To compare the performance of 3D magnetic resonance imaging (MRI) in conjunction with an intravascular contrast agent with that of scintigraphy, with respect to detection and localisation of gastrointestinal haemorrhage in vivo in pigs. METHODS Intraluminal bleeding sites were surgically created in the small bowel and colon of six pigs. The animals underwent scintigraphy w...

OBJECTIVE To review practice of massive primary postpartum haemorrhage management and develop a protocol. METHODS Cross-sectional study conducted at the Department of Obstetrics and Gynaecology at Aga Khan University Hospital, Karachi between January 1, 2003 and July 31, 2004. Women with primary postpartum haemorrhage and had blood loss > or = 1000ml were included in the study. Medical record...

Approximately 90% of patients with cirrhosis will have developed gastro-oesophageal varices within 10 yr. Oesophageal variceal haemorrhage is a devastating complication of cirrhosis with mortality as high as 25–50%. Therefore, prophylactic measures before the first bleed are crucial. If patients survive a variceal bleed, there is approximately a 70% risk that they will have a further bleed with...

Haemorrhage from oesophageal varices is a life threatening emergency with a mortality rate in the order of 30%-50%. In the last three decades there have been many advances in the treatment and prevention of variceal bleeding. Over recent years the introduction of new pharmaceutical agents that reduce portal pressure, endoscopic variceal ligation, transjugular intrahepatic portosystemic shunt, a...