The evaluation and control of the trains induced vibrations needs even more attention in the case of underground tracks which passes near to monuments and historical sites. The rail corrugations which occur due to the wheels’ impulse loads during the operation period of underground railway tracks, usually amplify the ground borne noise and vibration. In the current study, the mentioned phenomen...

progressive collapse is defined as the spread of an initial failure from element to element, eventually resulting in the collapse of an entire structure or a disproportionately large part of it. the current progressive collapse analyses and design methods in guidelines and codes focus on the alternate load path method. this method is suitable especially in the case of blast-induced progressive ...

Explosions occur in military conflicts as well as in various industrial applications. Air blast waves generated by large explosions move outward with high velocity, pressure and temperature. The blast waves not only incapacitate military and civilian personnel, but also damages buildings, vehicles, and other properties. Hence, there has been extensive research on how to mitigate blast wave effe...

Progressive collapse is defined as the spread of an initial failure from element to element, eventually resulting in the collapse of an entire structure or a disproportionately large part of it. The current progressive collapse analyses and design methods in guidelines and codes focus on the alternate load path method. This method is suitable especially in the case of blast-induced progressive ...

The advent of Bcr-Abl tyrosine kinase inhibitors (TKI) has revolutionized the treatment of chronic myelogenous leukemia (CML). However, resistance evolves due to BCR-ABL mutations and other mechanisms. Furthermore, patients with blast crisis CML are less responsive and quiescent CML stem cells are insensitive to these inhibitors. We found that triptolide, a diterpenoid, at nanomolar concentrati...

Some existing concrete structures not only face threats of possible explosions and impact, but also suffer from long-term fatigue loads induced by traffic or vibration machines. Researchers have conducted extensive investigations on against highly dynamic load, e.g., blast impact. However, the damage performance deterioration flexural members due to cyclic throughout service life been considere...