Perinatal hypoxic-ischemic (HI) encephalopathy is one of the main causes of mortality and long-term disabilities in newborns. The adverse effect of birth asphyxia (deprivation of oxygen and glucose) in the brain can be devastating, resulting in death or severe neurological consequences such as mental retardation, learning disabilities, epilepsy and cerebral palsy. In spite of the advances in ne...

BACKGROUND The influence of rural-urban disparities in children's health on neonatal death in disadvantaged areas of China is poorly understood. In this study of rural and urban populations in Gansu province, a disadvantaged province of China, we describe the characteristics and mortality of newborn infants and evaluated rural-urban differences of neonatal death. METHODS We analyzed all neona...

OBJECTIVE To compare the rates and aetiologies of stillbirth over the past 50 years. STUDY DESIGN We reviewed all autopsy reports for stillbirths occurring between 1989 and 2009 at the McGill University Health Centre to determine the pathological aetiology of stillbirths. We also reviewed maternal characteristics. We compared our results with a previous study published in 1992 on aetiologies ...

BACKGROUND Prior studies have shown that using uterotonics to augment or induce labor before arrival at comprehensive Emergency Obstetric and Neonatal Care (CEmONC) settings (henceforth, "outside uterotonics") may contribute to perinatal mortality in low- and middle-income countries. We estimate its effect on perinatal mortality in rural Bangladesh. METHODS Using hospital records (23986 singl...

Acute perinatal asphyxia is a major cause of death and neurological injury in newborn infants. Severe asphyxia can occur in infants around the time of birth for several reasons. The aim of our study was to find the most sensitive, easily obtainable and fast assessable parameter of the presence and quantification of asphyxia.In our study 39 term newborns (15 healthy term newborns and 24 asphyxia...