Background: High-quality oligonucleotides for molecular amplification and detection procedures of diverse target sequences depend on sequence homology. Processing input identifying homogeneous regions in alignments can be carried out by hand only if they are small contain high similarity. Finding the best large inhomogeneous needs to automated. Results: The ConsensusPrime pipeline was developed...

CYP719A14 structure analysis and its interaction with ligands via bioinformatic methods. Methods. Homologous modeling of three-dimensional enzyme. Molecular docking. Results. enzyme, which shows cheilanthifoline synthase activity, model was build based on results homologous modeling. Interaction built possible substrates – benzylisoquinoline compounds: (S)-Scoulerine, (S)-Cheilanthifoline, (S)-...