Carbon nanomaterials (CNMs) are a fascinating class of materials that have gained considerable interest in recent years. Their favourable biocompatibility, combined with unique chemical and mechanical properties, has attracted scientists from various disciplines. A significant hurdle their deployment biomedical applications is hydrophobicity pristine form. This review surveys discusses existing...

Surfaces covered with polyethylene glycol (PEG; HO-(CH(2)-CH(2)-O)(n)-H) have been shown to be biocompatible because PEG's properties yield nonimmunogenicity, nonantigenicity, and protein rejection. To produce a biocompatible surface coating, we have developed a method for grafting PEG onto activated silica films. We first deposited an amorphous silica film by plasma-enhanced chemical vapor dep...

Manufacturing new Hepatitis B virus vaccines, specifically by the use of nanoparticles, is of high global interest. In this paper, a new biocompatible and biodegradable structure of nano-sized hepatitis B virus’ surface antigen (HBsAg) was generated by conjugation with dendrimers, a low cost biodegradable and biocompatible polymer. The physicochemical properties of the conjugate were characteri...

In 1978, a simplified technique for peritoneal dialysis (PD) using plastic bags and glucose as osmotic agent allowed PD to become accepted as a home-based renal replacement therapy. However, PD was marred by complications including peritonitis and loss of function of the peritoneal membrane. Both complications may be favored by the bioincompatibility of PD solutions. The composition of PD solut...

Single-cell analysis has become increasingly important in uncovering cell heterogeneity, which great implications medicine and biology for a deep understanding of characteristics. Owing to its significance, it is vital create novel devices that can reveal special or unique cells. In this work, we developed single-cell secretion detection chip consisting microwells trap single Each well surround...

Candida albicans is an emerging multidrug-resistant opportunistic pathogen representing important source of invasive disease in humans and generating high healthcare costs worldwide. The development a rapid simple antifungal susceptibility test (AFST) could limit the spread this disease, increase efficiency treatment, lower risk developing resistant strains. We developed microfluidic chip conta...

This project focused on the growth of Cu2O nanocubes in microwells from nanoparticle “seeds.” The seeds were first formed by the reduction of copper sulfate with ascorbic acid in the presence of the surfactant poly(ethylene glycol) (PEG). Upon reaction within the microwell, the seed solution formed a larger single crystal. By varying the amount of precursor seed particles available in the react...