The national neonatal screening programme in the United Arab Emirates currently includes 16 disorders: congenital hypothyroidism, sickle-cell diseases, congenital adrenal hyperplasia, biotinidase deficiency and 12 amino acid, organic acid and fatty acid disorders. This paper reports data since the programme started in January 1995 up to December 2011 on the incidence of screened disorders and t...

Functional gastrointestinal (GI) disorders are collections of symptoms attributable to the GI tract in the absence of mucosal, structural, or biochemical disease. Two of the most common disorders, chronic constipation and irritable bowel syndrome (IBS), have common etiopathogenetic features—notably psychosocial disturbances, dysmotility, and heightened sensitivity. In some patients with IBS, th...

Activation of lipid peroxidation due to a disorder redox homeostasis in dogs with comorbidity babesiosis and dirofilariasis causes the involvement not only components hepatorenal system, but also cardiopulmonary system pathological process against background development intoxication hypoxic phenomena hepatocytes cardiomyocytes. As result conducted biochemical studies blood sick animals, it was ...

AIM To find the association between biochemical hypoglycemia on a 2-hour screening oral glucose tolerance test (OGTT) and insulin resistance. METHOD Subjects of this study were sampled from the China National Diabetes and Metabolic Disorders Study that was conducted during 2007 and 2008. Blood samples were drawn at 0, 30, and 120 minutes after the glucose load. Biochemical hypoglycemia was de...

introduction: functional gastrointestinal disorders (fgid) are non-fatal, unknown etiology disorders with absence of a structural or biochemical explanation and accounting for up to 50% of gastroenterology referrals. infant regurgitation, rumination and cyclic vomiting constitute the vomiting disorders. abdominal pain disorders are classified as: functional dyspepsia, irritable bowel syndrome (...

multiple sclerosis (ms) is a demyelinating disease of the central nervous system characterized by morphological hallmarks of inflammation, demyelination and axonal loss. to date, little attention has been paid to the contribution of mitochondrial respiratory chain enzyme activities to ms. in this study, kinetic analysis of mitochondrial respiratory chain complex i enzyme (measured as nadh ferri...

Dairy cows are exposed to numerous hematological and biochemical changes, particularly in late gestation and early lactation. Various factors influence a metabolic profile in animals. Reliable indicators of metabolic profile and health status of dairy cows in peripartum period are haematological and biochemical parameters. A transitional period in dairy cows is followed by physiological, metabo...

A number of cellular and biochemical processes are involved in the pathophysiology of glomerular and vascular remodeling, leading to renal and vascular disorders, respectively. Although estradiol protects the renal and cardiovascular systems, the mechanisms involved remain unclear. In this review we provide a discussion of the cellular, biochemical, and molecular mechanisms by which estradiol m...

The biochemical bases of the placebo effect are still incompletely known. We show here that the placebo effect in Parkinson's disease is due, at least in part, to the release of dopamine in the striatum. We propose that the placebo effect might be related to reward mechanisms. The expectation of reward (i.e. clinical benefit) seems to be particularly relevant. According to this theory, brain do...