Abstract Smoke-derived seed germination is an important trait for plants to colonize postfire habitats. The well-characterized smoke-derived chemicals of karrikins germinate seeds species not known occur after fires in nature. Hence, the ecologically relevant cues smoke remain be explored native plants. With fire-chaser, Nicotiana attenuata , we revisit a bioassay-driven fractionation liquid id...

INTRODUCTION Diabetes mellitus is a highly prevalent chronic progressive disease with complications that include diabetic-foot ulcers. METHODS Enterococci isolated from diabetic-foot infections were identified, evaluated by macro-restriction analysis, and screened for virulence traits and antimicrobial resistance. RESULTS All isolates were considered multidrug-resistant, cytolysin and gelat...

Introduction: Bioassay is necessary for assessment of pollution. Because physical and chemical taste are not enough for assessment of potential effects on water ecosystem. Bioassay tests have alot of scientific value inanition doing of them is easy and need less time, also need less space, laboratory equipment’s and expenditure. Therefor such tests have found special attention in water pollutio...

BACKGROUND There are three main problems associated with the virtual screening of bioassay data. The first is access to freely-available curated data, the second is the number of false positives that occur in the physical primary screening process, and finally the data is highly-imbalanced with a low ratio of Active compounds to Inactive compounds. This paper first discusses these three problem...

An integrated series of studies was presented in which several factors were assessed as to their capability to influence the outcome of carcinogenicity of benzidine dihydrochloride in mice. In all studies C57BL/6J X C3HeB/FeJ F1 mice of both sexes were utilized. Animals were either 6 or 1 week of age at the beginning of carcinogenic treatment. Six-week-old mice were exposed to p.o. administrati...

The Spheres of Influence, “Assessing Assays” (Schmidt 2002), in the May 2002 issue of EHP criticizes the National Toxicology Program rodent bioassay (NTPRB) without discussing its importance in regulation and public health. The Spheres article (Schmidt 2002) does not express concern for the validity of alternative transgenic methods proposed to replace the NTPRB for detecting carcinogens. By fo...