Curcumin protects the skin against radiation-induced epidermal damage and prevents morphological changes induced by irradiation skin, thereby maintaining the epidermal thickness and cell density of basal layers. In this study, the effects of topical curcumin treatment on radiation burns were evaluated in a mini-pig model. Histological and clinical changes were observed five weeks after radiatio...

Mast cell production of interleukin-10 (IL-10) can limit the skin pathology induced by chronic low-dose ultraviolet (UV)-B irradiation. Although the mechanism that promotes mast cell IL-10 production in this setting is unknown, exposure of the skin to UVB irradiation induces increased production of the immune modifying agent 1alpha,25-dihydroxyvitamin D(3) (1alpha,25[OH](2)D(3)). We now show th...

Histopathological changes in the dorsal skin of hairless descendants of Mexican hairless dogs (MHDs) exposed to artificial irradiation with high energy dose (180 kJ/m2) of ultraviolet (UV) rays (UVA + B) were investigated. Macroscopically, erythema and edema were observed in the irradiated skin at 1 day after irradiation (DAI), and blister formation occurred except one dog at 2 DAI. Erythema al...

Background: Topical application of 1a, 25-dihydroxyvitamin D3 (1-a,25-(OH)2D3) inhibits7, 12-dimethylbenz [a] anthracene (DMBA) and 12-a-tetradecanoylphorbol-13-acetate (TPA)-induced tumor formation of mouse skin. Ultraviolet irradiation (UV) may also induce skin tumors. However, no report exists regarding the effect of topical active vitamin D3, tacrolimus, or corticosteroids on UV-irradiation...

Monolithically integrated emitters have been increasingly applied to microfluidic devices that are coupled to mass spectrometers (MS) as electrospray ionization sources (ESI). A new method was developed to fabricate a duplicable structure which integrated the emitter into a poly(dimethylsiloxane) chip corner. Two photoresist layers containing a raised base which guaranteed the precise integrati...

Skin aging can be attributed to photoaging (extrinsic) and chronological (intrinsic) aging. Photoaging and intrinsic aging are induced by damage to human skin attributable to repeated exposure to ultraviolet (UV) irradiation and to the passage of time, respectively. In our previous report, eicosapentaenoic acid (EPA) was found to inhibit UV-induced matrix metalloproteinase-1 (MMP-1) expression ...

Abstract Photostimulated luminescence allows energy or data to be stored and released using electromagnetic waves as both the input output, has attracted considerable interest in fields of biomedical information technologies. However, this phenomenon is mostly limited solid inorganic materials. Here, we report photostimulated from purely organic blend films, composed electron donor, acceptor, t...

When attacked by insects, plants release mixtures of volatile compounds that are beneficial for direct or indirect defense. Natural variation of volatile emissions frequently occurs between and within plant species, but knowledge of the underlying molecular mechanisms is limited. We investigated intraspecific differences of volatile emissions induced from rosette leaves of 27 accessions of Arab...

1. The response of 25-hydroxyvitamin D [25(0H)Dl to artificial ultraviolet irradiation applied to a known area of dorsal skin was investigated in 18 subjects, small quantities of ultraviolet energy being used. Ultraviolet irradiation was administered on days, 1,3,5,8, 10, 12, 15 and 17, a total of 15 min being delivered over this time. In 15 subjects plasma 25-(0H)D showed a significant increas...