A simple, selective and sensitive high-performance liquid chromatographic method with fluorescence detection is described for the simultaneous determination of catecholamines and 5-hydroxyindoleamines. The method is based on the derivatization of the amines with benzylamine in the presence of potassium hexacyanoferrate(III) under mild conditions. The resulting fluorescent derivatives are separa...

Abstract: Flavoprotein monoamine oxidase is located on the outer membrane of mitochondria. It catalyzes oxidative deamination of monoamine neurotransmitters such as serotonin, norepinephrine and dopamine and hence is a target enzyme for antidepressant drugs. MAO (mono amine oxidase) has two isoforms, namely MAO-A and MAO-B. MAO-A isoform has higher affinity for serotonin and norepinephrine, whi...

A novel complex of cadmium (II) picrate (pic) with V-shaped ligand bis(N-allylbenzimidazol-2-ylmethyl)benzylamine (babb), with composition [Cd(babb)(2)](pic)(2), was synthesized and characterized by elemental analyses and electrical conductivity, IR, and UV/visible spectra. The crystal structure of the complex has been determined by the single-crystal X-ray diffraction. In the complex, the coor...

1. The action of N-2'-chloroethyl-N-ethyl-2-methyl benzylamine (xylamine) on rat pineal gland sympathetic innervation was examined. 2. This alkylating agent caused a concentration-dependent increase in pineal gland N-acetyltransferase (NAT) activity in neurologically intact pineal glands that was suppressed in glands previously subjected to bilateral superior cervical ganglionectomy. 3. Xylamin...

In this paper we describe a highly sensitive and selective LC method for the determination of 5-hydroxyindoles (serotonin, N-acetylserotonin, 5-hydroxyindole-3-acetamide, 5-hydroxytryptophan, 5-hydroxyindole-3-acetic acid, 5-hydroxytryptophol) through post-column electrochemical derivatization fluorescence detection. These can be separated within 40 min by reversed-phase liquid chromatography u...

The novel N-(3,5-bis(trifluoromethyl)benzyl)stearamide 3 was prepared in moderate yield by a solventless direct amidation reaction of stearic acid 1 with 3,5-bis(trifluoromethyl)benzylamine 2 at 140 °C for 24 h under metal- and catalyst-free conditions. This practical method conducted air without any special treatment or activation. fatty amide fully characterized IR, UV–Vis, 1D 2D NMR spectros...

Moringa oleifera is a relatively well-studied ethnobotanical species, but information limited regarding its stem anatomy and the production potential of phytochemicals from bark tissue. Knowing that variation exists in chemical defenses by plants with growing conditions developmental stages, M. was grown under controlled to characterize tissues determine if contained correct phytochemical compo...

N a z m i A . K a s s a b , S a n a a 0 . A b d A l l a h , a n d S a i d A . E l b a h a i i Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt Z. Naturforsch. 34b, 507-510 (1979); received September 28, 1978 Arylhydrazonorhodanines, Arylhydrazonoisorhodanines, Ring Cleavage, Triazolinones, Alkylation The 5-arylhydrazono derivatives of rhodanine and isorhodanine were su...