Absract   Intracranial invasion of cellular blue nevus (CBN) from the skin is extremely rare   and such a condition with malignant transformation is even rarer. A case of   meningeal melanoma with malignant transformation which was derived from an Ota   nevus is presented in this report.   A21-year-old man with a neurocutaneous syndrome since childhood was referred   with headache and mild le...

I read with interest the paper by Maldonado et al. ( 1 ) investigating the distribution of BRAF mutations across different melanoma types. One of the questions addressed by the authors was whether cutaneous melanomas with a BRAF mutation arose from preexisting melanocytic nevi. In an analysis of 46 lesions, they found melanomas with an associated nevus to have only a slightly higher prevalence ...

A 9-year-old boy had had a large nevus of the scalp since birth. When he was 3 years old, the nevus was excised. The histologic diagnosis was cellular blue nevus. Two years later a follow-up CT scan showed a high-density mass in the base of right middle cranial fossa (Fig . 1). Coronal CT scan showed an extracranial extension of the tumor through the right petrosal bone. Partial removal of the ...

OBJECTIVE To report the clinical evolution and handling of a Spitz nevus, from its initial flat feature to becoming an irregular, nodular, reddish lesion. CASE DESCRIPTION Female child, phototype II, with a small congenital nevus on the left lower limb and other sustained small nevi. The patient went through annual clinical and dermoscopic evaluations between the ages of three and seven, peri...

AIM The aim of this study is to report a clinical case of oral nevus. BACKGROUND Nevus is a congenital or acquired benign neoplasia that can be observed in the skin or mucous membranes. It is an uncommon condition in the oral mucosa. When it does occur, the preferred location is on the palate, followed by the cheek mucosa, lip and tongue. CASE REPORT In this case study, we relate the diagno...

Mucinous nevus is a very rare entity and can be classified as both a cutaneous mucinosis and a connective tissue nevus. We describe the clinicopathologic features of an unusual case of mucinous nevus in a 9-year-old Taiwanese boy who presented with multiple grouped flesh-colored nodules with band-like distribution on his right thigh since birth. Histopathological examination of the skin lesion ...

The intention of this review on nevus comedonicus (NC) is to update on clinical features, pathogenesis, and therapy. NC is a rare epidermal nevus type. It is part of the nevus comedonicus syndrome, a neurocutaneous disorder with ocular, skeletal, and central nervous symptoms. Recently, acne-related signaling pathways and somatic mutations of tyrosine kinase receptors have been identified and ma...

1. Sugarman JL. Epidermal nevus syndromes. Semin Cutan Med Surg. 2007;26:221-30. 2. Solomon LM, Fretzin DF, Dewald RL. The epidermal nevus syndrome. Arch Dermatol. 1968;97:273-85. 3. Solomon LM, Esterly NB. Epidermal and other congenital organoid nevi. Curr Provi Pediatr. 1975;6:1-56. 4. Singal A, Dhaliwal U, Bhattacharyya SN , Rohatgi J, Singh N. Complex ocular choristomas in linear nevus seba...

The authors report a rare case of primary orbital melanoma (POM) combined with giant divided nevus of the eyelid. An 8-year-old Chinese girl is referred for evaluation of 2-month duration of exophthalmos with decreased vision, epiphora, and pain on her right eye. His presentation, imaging, biopsy, histopathology, and management are presented. The possible cellular origin of the POM and the rela...

Divided nevus, also known as kissing nevus, is a rare variant of congenital melanocytic nevi in which there are two adjacent nevi in areas of the body that undergo embryonic cleavage. The original description of this type of lesion was on the eyelid. The location on the penis is even rarer, with only 17 case reports in the literature so far, and only one of them described the dermoscopic findin...