Acupuncture has a positive effect on cognitive deficits. However, the effects of laser acupuncture (LA) on cognitive function and its mechanisms of action are unclear. The present study aimed to evaluate the effects of LA on middle cerebral artery occlusion- (MCAO-) induced cognitive impairment and its mechanisms of action. Transient focal cerebral ischemia was modeled in adult Sprague-Dawley r...

Bax and Bak, two pro-apoptotic Bcl-2 family proteins, have been implicated in acute kidney injury following renal ischemia/reperfusion; however, definitive evidence for a role of these genes in the disease process is lacking. Here we first examined two Bax-deficient mouse models and found that only conditional Bax deletion specifically from proximal tubules could ameliorate ischemic acute kidne...

Hot pepper is one of the economically important crops in Asia. A large number of gene sequences, including expressed sequence tag (EST) and genomic sequences are publicly available. However, it is still a daunting task to determine gene function due to difficulties in genetic modification of a pepper plants. Here, we show the application of the virus-induced gene silencing (VIGS) repression for...

Background: Cancer treatment methods can lead to male infertility .in this regard, cryopreservation of spermatogonial stem cells (SSC) and cell-to-person transplantation after the course of treatment to resolve the problem of infertility is a good one. The cryopreservation of SSC is an important process as it can help on the return of spermatogenesis. However, during this process, the stem cell...

In the present study, A2780 CP and SKOV-3 cells, relevant to ovarian cancer granulosa as normal were evaluated through cold atmospheric plasma (CAP) directly, indirectly, by a concomitant modality of plasma-activated medium (PAM) with common drugs overcome chemotherapy resistance in cancer. Our results confirm high potential PAM comparison CAP for selected cell lines, selectivity mechanism was ...

Abstract: Background and Objectives: In nanotechnology, biosynthesis of nanoparticles has gained considerable attention. Development synthesis plant based metallic with improved properties less undesirable effects have many advantages over the conventional methods. addition to performing their intended function, these phyto antioxidant functionalized can protect against oxidative damage. Pergul...