The blood-brain barrier is an evolutionary ancient structure that provides direct support and protection of the nervous system. In all systems, it establishes a tight diffusion barrier that hinders uncontrolled paracellular diffusion into the nervous system. In invertebrates, the blood-brain barrier separates the nervous system from the hemolymph. Thus, the barrier-forming cells need to activel...

ÐIn this paper, we propose an efficient barrier synchronization scheme on networks with arbitrary topologies. We first present a distributed method in building a barrier routing tree. The barrier messages can be delivered adaptively according to the hierarchy of the established barrier tree to void congestion and faulty nodes in the network. We then propose a new technique, called bandwidth-pre...

in the present work, impact of lewis acid (la) catalysts bf3, bcl3, and bbr3 on the kinetics andregioselectivity of 1,3-dipolar cycloaddition (1,3-dc) reaction between azidobenzene and acroleinwas theoretically studied using b3lyp/6-31g* level. our results indicate while the uncatalyzed 1,3-dc reaction under investigation takes place via a non-polar, non-regioselective, and lowasynchronous proc...

we describe a simple model that fits well with iranian economy, and extends a methodology which chary at el. (2007) demonstrated. in addition to four traditional wedges, we introduce additional trade wedge. we then evaluate the contribution of these wedges to the fluctuations in iran during last three years. because of international sanction, trading cost increases, and firms have difficulty to...

A mixture of sphingolipids, cholesterol, and free fatty acids forms the intercellular membrane bilayers of the stratum corneum which are presumed to regulate epidermal barrier function. Prior studies have shown that both cholesterol and fatty acid synthesis are rapidly regulated by epidermal barrier requirements. In contrast, the importance of sphingolipids in barrier function has not been dire...

Acquisition of epidermal barrier function occurs late in mouse gestation. Several days before birth a wave of barrier acquisition sweeps across murine fetal skin, converging on dorsal and ventral midlines. We investigated the molecular pathways active during epidermal barrier formation. Akt signaling increased as the barrier wave crossed epidermis and Jun was transiently dephosphorylated. Inhib...

Barrier coverage, an important research area with respect to camera sensor networks, consists of a number of camera sensors to detect intruders that pass through the barrier area. Existing works on barrier coverage such as local face-view barrier coverage and full-view barrier coverage typically assume that each intruder is considered as a point. However, the crucial feature (e.g., size) of the...

As network latency rapidly approaches thousands of processor cycles and multiprocessors systems become larger and larger, the primary factor in determining a barrier algorithm’s performance is the number of serialized network latencies it requires. All existing barrier algorithms require at least round trip message latencies to perform a single barrier operation on an -node shared memory multip...

The payoff of a barrier option depends on whether or not a specified asset price, index, or rate reaches a specified level during the life of the option. Most models for pricing barrier options assume continuous monitoring of the barrier; under this assumption, the option can often be priced in closed form. Many (if not most) real contracts with barrier provisions specify discrete monitoring in...

We analytically study the dynamics of evolving populations that exhibit metastability on the level of phenotype or fitness. In constant selective environments, such metastable behavior is caused by two qualitatively different mechanisms. On the one hand, populations may become pinned at a local fitness optimum, being separated from higher-fitness genotypes by a fitness barrier of low-fitness ge...