Prolonged residence of drug formulation in the nasal cavity is important for the enhancing intranasal drug delivery. The objective of the present study was to develop a mucoadhesive in-situ gelling nasal insert which would enable the reduced nasal mucociliary clearance in order to improve the bioavailability of metoclopramide hydrochloride. Metoclopramide hydrochloride is a potent antiemetic...

xanthan gum is an extracellular polysaccharide produced by various xanthomonas species such as x. campestris . the objective of present study was to investigate the influence of different carbon and nitrogen sources on xanthan gum production by x. campestris . using an experimental response surface methodology (rsm) complemented with a central composite design (ccd), the impact of peptone, lact...

Objective: Several diseases are reported to be uncommon in those parts of the world where dietary fiber intakes are high, therefore, in this study; we evaluated the hypocholesterolemiceffects of a dietary fiber (guar gum) in hypercholesteromic rats. Materials and Methods: Rats were fed high-fat or a normal fed diet for 12-week then treated with 5% guar gum in their regime during a 28 days peri...

PURPOSE We aimed to examine the effect of gum chewing after laparoscopic colorectal cancer surgery. METHODS We reviewed the medical records of patients who underwent laparoscopic colorectal cancer surgery in Incheon St. Mary's Hospital, The Catholic University of Korea School of Medicine. We divided the patients into 2 groups: group A consisted of 67 patients who did not chew gum; group B con...

The aim of this work was to evaluate the physicochemical properties of fresh foams based on egg white proteins, xanthan gum and gum Arabic. The distributions of the size of gas bubbles suspended in liquid were determined, as well as density and volume fraction of gas phase of the generated foams. Additionally, the viscoelastic properties in the linear range were measured, and the results were a...

OBJECTIVE To assess the effectiveness of an outreach health adviser on treatment, partner notification and outcome for clients diagnosed with genital chlamydia (CT) infection at a community young people's clinic. METHODS From August 1999 to March 2000, a genitourinary medicine (GUM) based health adviser helped to develop testing and undertook outreach management of clients aged under 26 years...

BACKGROUND /st> Airway Scope is a new videolaryngoscope which requires less cervical movement during intubation than direct laryngoscopy. Thus, in patients wearing a rigid cervical collar, we compared the efficacy of the Airway Scope and the gum elastic bougie with Macintosh laryngoscope during tracheal intubation. METHODS /st> Anaesthesia was induced with propofol, fentanyl, and rocuronium. ...

OBJECTIVE In the recent years, herbal oral hygiene products have gained increasing attention. The aim of this study was to assess the effects of three types of mastic gums on the level of Mutans streptococci, Lactobacilli and pH of the saliva. MATERIALS AND METHODS Forty-two students in the age range of 20-30 years were divided into three parallel groups; each of them separately used pure mas...

Eight-month-old Sprague-Dawley rats were fed on diets containing dietary fiber at the 5% level for 3 weeks to examine the effect on the lipid metabolism and immune function. Among cellulose, guar gum, partially hydrolyzed guar gum (PHGG), glucomannan and highly methoxylated pectin, guar gum induced a significant decrease in the food intake and weight gain, as well as a significant increase in t...

Purpose: To compare the mucoadhesive performance of grewia polysaccharide gum with those of guar gum, carboxymethylcellulose, hydroxypropyl methylcellulose and carbopol 971P. Methods: Grewia polysaccharide gum compacts or gels as well as those of guar gum, carboxymethylcellulose, hydroxypropyl methylcellulose or carbopol 971P were prepared. Texturometric and tensile analysis of the polymer gels...