Ischemic preconditioning (IP) is a well-established phenomenon, and the underlying mechanisms of IP are thought to involve adaptive changes within the injured tissue. Because one of the main functions of immune cells is to harbor memory, we hypothesized that circulating immune cells could mediate IP by responding to an initial ischemia reperfusion injury (IRI) and then mediate decreased injury ...

BACKGROUND/AIMS The chromatin remodeler DAXX, a predominantly nuclear protein, regulates the status of chromatin organization. The aim of this exploratory immunohistochemical study was to evaluate DAXX protein expression in high grade invasive urothelial carcinoma (UC) of the bladder as a biological regulator of aggressiveness. METHODS Quantitative analysis was made on DAXX immunostained nucl...

OBJECTIVE To present the perioperative outcomes from the British Association of Urological Surgeons (BAUS) nephrectomy dataset for 2012, the first year of public reporting of individual surgeon outcomes in the UK. PATIENTS AND METHODS All nephrectomies performed in the year 2012 and recorded in the database were analysed. These were divided into simple nephrectomy (SN), partial nephrectomy (P...

We study the distribution function P (rho) of the effective resistance rho in two- and three-dimensional random resistor networks of linear size L in the hopping percolation model. In this model each bond has a conductivity taken from an exponential form sigma proportional to exp (-kappar) , where kappa is a measure of disorder and r is a random number, 0< or = r < or =1 . We find that in both ...

We investigate the performance of Brownian motors in environments governed by the "porous medium" equation partial differential(t)rho = D partial differential(x) (rho(nu-1) partial differential(x)rho), where rho is the density and D and nu positive constants. This nonlinear equation yields anomalous diffusion when nu not = 1: subdiffusion for nu > 1 and superdiffusion for nu < 1. The thermal ra...

We introduce the NU-MBROLA project as an extension of the MBROLA project for designing large NU-MBROLA databases exhibiting the same properties as MBROLA diphone databases, without the restriction of being composed of diphones. The accompanying NU-MBROLA synthesizer implements the MBROLA algorithm on speech segments only defined by their starting and ending points in natural speech files. It is...

We derive a model-independent upper bound on the scale of Majorana-neutrino mass generation. The upper bound is 4pi (nu2)/square root3 m(nu), where nu approximately 246 GeV is the weak scale and m(nu) is the Majorana-neutrino mass. For neutrino masses implied by neutrino oscillation experiments, all but one of these bounds are less than the Planck scale, and they are all within a few orders of ...