Recently, the effects of antimicrobial activity of silver nanoparticles was considered by researcher because of Bacterial resistance to antimicrobial agents in chemical.The aim of this study was to evaluate the antimicrobial activity of the gold nanoparticles on Escherichia coli. Gold nanoparticles are chemically synthesized. Standard strain of E. coli was cultured in a nutrient broth. Minimum ...

New antibiotics with novel mechanisms of action are urgently needed to overcome the growing bacterial resistance problem faced by clinicians today. PC190723 and related compounds represent a promising new class of antibacterial compounds that target the essential bacterial cell division protein FtsZ. While this family of compounds exhibits potent antistaphylococcal activity, they have poor acti...

The concept of phage therapy to treat bacterial infections was born with the discovery of the bacteriophage almost a century ago. After a chequered history, its current renaissance is fueled by the dangerous appearance of antibiotic-resistant bacteria on a global scale. As a mark of this renewed interest, the unanswered problems of phage therapy are now being addressed, especially for human use...

A prototypical patient is presented to introduce important design issues for clinical trials of antibacterials in the treatment of ventilator-associated bacterial pneumonia.

Background: Pleural empyema is a collection of purulent exudate between the lungs and the chest wall. Despite the importance of the disease in children, no study has investigated it in Mazandaran province, Iran. The aim of this study was to evaluate the prevalence, clinical manifestations, diagnosis, treatment and its outcome in children referring to hospitals of Mazandaran during 12 years. Ma...

objective conjunctivitis is a common disease in neonates. several bacterial and viral infectious agents may cause it. tear circulation and blinking has protective effects from bacterial colonization in the conjuntival sac. reduced blinking increases the possibility of bacterial conjunctivitis. we studied the effect of eye patches on bacterial colonization of the conjunctival sac.  methods in 10...

Definition and Terminology The term “croup syndrome” refers to a group of diseases that varies in anatomic involvement and etiologic agents and includes laryngotracheitis, spasmodic croup, bacterial tracheitis, laryngotracheobronchitis, and laryngotracheobronchopneumonitis. Although the terms “laryngotracheitis” and “laryngotracheobronchitis” frequently are used interchangeably in the literatur...

background: acute bacterial meningitis is among serious infections of the central nervous system (cns). the early diagnosis and empiric antibiotic treatments have led to a reduction in morbidity and mortality rates. pcr and the enzymatic digestion of 16s rdna fragment following the pcr by universal primers led up fast and sensitive determination. the aims of the present study was to improve our...

Sulfonamides and their different derivatives are extensively used in therapy due to their pharmacological properties. Sulfa drugs were amongst the oldest synthesized antimicrobial agents and are still widely used today to treat different microbial infections. Clinical treatment with sulfonamides has regained confidence with the use of a combination of sulfamethoxazole and trimethoprim to treat ...

background: wound infections are associated with increased morbidity and mortality. etiologic agents of wound infections vary with geographical locations. this study was conducted to assess the prevalence of wound infections, the effect of age and gender on the prevalence as well as the etiologic agents and their susceptibility to antibacterial agents. methods: wound swabs collected from 2061 p...