نتایج جستجو برای: background selection

تعداد نتایج: 1130158  

Journal: :middle east journal of cancer 0
amirehsan lashkari department of bio-medical engineering, institute of electrical engineering & information technology, iranian research organization for science and technology (irost), tehran, iran

background: in this paper we compare a highly accurate supervised to an unsupervised technique that uses breast thermal images with the aim of assisting physicians in early detection of breast cancer. methods: first, we segmented the images and determined the region of interest. then, 23 features that included statistical, morphological, frequency domain, histogram and gray-level co-occurrence ...

All living organisms are exposed to ionizing radiation comprising cosmic rays coming from outer space, terrestrial nuclides occurring in the earth’s crust, building materials, air, water and foods and in the human body itself. The exposures are constant and uniform for all individuals everywhere including the dose from ingestion of 40K in food. Cosmic rays are, more intense at higher alt...

Journal: :Improving Schools 2006

2014
Carmen Amador Ben J Hayes Hans D Daetwyler

Critically endangered breeds and populations are often crossed with more common breeds or subspecies. This results in genetic admixture that can be undesirable when it challenges the genetic integrity of wild and domestic populations, causing a loss in special characteristics or unique genetic material and ultimately extinction. Here, we present two genomic selection strategies, using genome-wi...

Journal: :Genetics 2007
Laurence Loewe Brian Charlesworth

Background selection involves the reduction in effective population size caused by the removal of recurrent deleterious mutations from a population. Previous work has examined this process for large genomic regions. Here we focus on the level of a single gene or small group of genes and investigate how the effects of background selection caused by nonsynonymous mutations are influenced by the l...

2016
Kristen K. Irwin Stefan Laurent Sebastian Matuszewski Louise Ormond Hyunjin Shim Claudia Bank Jeffrey D. Jensen

21 22 Many features of viral populations make them excellent candidates for 23 population genetic study, including a very high rate of mutation, high levels of 24 nucleotide diversity, exceptionally large census population sizes, and frequent 25 positive selection. However, these attributes also mean that special care must 26 be taken in population genetic inference. For example, highly skewed ...

Journal: :Genetics 1995
D Charlesworth B Charlesworth M T Morgan

Stochastic simulations of the infinite sites model were used to study the behavior of genetic diversity at a neutral locus in a genomic region without recombination, but subject to selection against deleterious alleles maintained by recurrent mutation (background selection). In large populations, the effect of background selection on the number of segregating sites approaches the effect on nucl...

2012
Khandakar M. Iftekharuddaula Muhammad A. Salam Muhammad A. Newaz Helal U. Ahmed Bertrand C. Y. Collard Endang M. Septiningsih Darlene L. Sanchez Alvaro M. Pamplona David J. Mackill

Marker assisted backcrossing has been used effectively to transfer the submergence tolerance gene SUB1 into popular rice varieties, but the approach can be costly. The selection strategy comprising foreground marker and phenotypic selection was investigated as an alternative. The non-significant correlation coefficients between ranking of phenotypic selection and ranking of background marker se...

2010
Ningxin Zhang Richard D. Cannon Barbara R. Holland Mark L. Patchett Jan Schmid

In many microbes rapid mutation of highly mutable contingency genes continually replenishes a pool of variant alleles from which the most suitable are selected, assisting in rapid adaptation and evasion of the immune response. In some contingency genes mutability is achieved through DNA repeats within the coding region. The fungal human pathogen Candida albicans has 2600 repeat-containing ORFs....

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