نتایج جستجو برای: b5

تعداد نتایج: 2878  

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2014
Eric F Johnson J Patrick Connick James R Reed Wayne L Backes Manoj C Desai Lianhong Xu D Fernando Estrada Jennifer S Laurence Emily E Scott

This report summarizes a symposium sponsored by the American Society for Pharmacology and Experimental Therapeutics at Experimental Biology held April 20-24 in Boston, MA. Presentations discussed the status of cytochrome P450 (P450) knowledge, emphasizing advances and challenges in relating structure with function and in applying this information to drug design. First, at least one structure of...

Journal: :The EMBO journal 2005
Silvia Brambillasca Monica Yabal Paolo Soffientini Sandra Stefanovic Marja Makarow Ramanujan S Hegde Nica Borgese

A large class of proteins with cytosolic functional domains is anchored to selected intracellular membranes by a single hydrophobic segment close to the C-terminus. Although such tail-anchored (TA) proteins are numerous, diverse, and functionally important, the mechanism of their transmembrane insertion and the basis of their membrane selectivity remain unclear. To address this problem, we have...

2014
M. M. Rashed

Gas-to-liquid (GTL) fuel is regarded as a promising alternative diesel fuel. It can be used either directly as a diesel fuel or in blends with petroleum-derived diesel or biodiesel. This study investigated the fuel properties, engine performance and exhaust emissions of B5 diesel, GTL fuel and their blends. The main fuel properties of the blended fuels showed a linear variation with the fractio...

Journal: :Bulletin of the World Health Organization 1999
S K Gupta R C Gupta A K Seth A B Gupta J K Bassin A Gupta

An epidemiological investigation was undertaken in India to assess the prevalence of methaemoglobinaemia in areas with high nitrate concentration in drinking-water and the possible association with an adaptation of cytochrome-b5 reductase. Five areas were selected, with average nitrate ion concentrations in drinking-water of 26, 45, 95, 222 and 459 mg/l. These areas were visited and house sched...

Journal: :Clinical and vaccine immunology : CVI 2009
Clement A Meseda Anne E Mayer Arunima Kumar Alonzo D Garcia Joseph Campbell Paul Listrani Jody Manischewitz Lisa R King Hana Golding Michael Merchlinsky Jerry P Weir

The immune response elicited by LC16m8, a candidate smallpox vaccine that was developed in Japan by cold selection during serial passage of the Lister vaccine virus in primary rabbit kidney cells, was compared to Dryvax in a mouse model. LC16m8 carries a mutation resulting in the truncation of the B5 protein, an important neutralizing target of the extracellular envelope form of vaccinia virus ...

Journal: :علوم باغبانی 0
سیدجواد موسوی زاده کامبیز مشایخی

abstract somatic embryogenesis is a new approach to in vitro plant propagation. this technique is based on stem cell obtain and its differentiation to a complete plant. this is affected by components of media culture. so, the effects of ms, b5 and nl media on carrot petiole somatic embryogenesis investigated via histological experiment. to do this, carrot petioles (with 1 cm dimension) cultured...

Journal: :Journal of medical genetics 1983
J S Daly D E Hultquist D L Rucknagel

A 25-year-old woman taking usual doses of phenazopyridine developed her third clinically significant episode of cyanosis. Life threatening methaemoglobinaemia was documented and was treated with methylene blue. The patient and several members of her family showed decreased activities of erythrocyte NADH-cytochrome b5 reductase, predisposing them to the development of clinically significant meth...

Journal: :Atlas of Genetics and Cytogenetics in Oncology and Haematology 2018

Journal: :Haematologica 2006
Roberto H Nussenzveig H Bindu Lingam Amos Gaikwad Qiqing Zhu Naijie Jing Josef T Prchal

We report here a novel mutation in the cytochrome b5 reductase gene resulting in type I methemoglobinemia. A single T->C transition in exon 8 at position 25985 was identified, changing codon 217 from Leu to Pro (L217P). The mutation is located in the NADH binding domain at the base of alpha-helix Nalpha3, a region of sequence highly conserved from yeast to man. A quantitative assessment of the ...

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