Bacterial meningitis is a severe illness with potentially dangerous consequences in any patient population. In the years from 2003 to 2007, children less than two years old had the highest estimated rate of bacterial meningitis of any age group. [1] In neonates, not only are the risks of infection profound – including death – the presentation can be atypical, making the likelihood of occult dis...

We have recently seen an unusual case of endophthalmitis secondary to Pasteurella multocida infection. Unlike previously reported cases this patient had no previous history of animal bites or scratch wounds. Treatment included subconjunctival, parenteral, and intravitreal administration of ampicillin. Although the eye was sterilised, the patient's vision remained poor owing to the extensive amo...

A 62-year-old patient with peritoneal dialysis (PD)-associated peritonitis is described. Identical strains of Pasteurella multocida and Streptococcus minor were cultured from the dialysate, and from the saliva of her recently adopted stray cat. Pasteurella is not often encountered as pathogen in PD-associated peritonitis, Streptococcus minor has never been cultured in human infection before. We...

in order to assess the immunopathological effects of aqueous echinacea purpurea extract (epe) on mice experimentally challenged with pasteurella multocida serotype a, forty female balb/c mice were randomly divided into four groups. the groups included a control group (received sterile distilled water 2 times/week for 2 weeks, intraperitoneally and then 100 μl sterile saline intranasally), a pma...

pasteurella multocida is known as one of the main organisms causing pneumonia in sheep. as immunity in pasteurellosis is serogroup specific, identification of prevalent capsular group among endemic areas is essential. the aim of this study was to molecular identification and determine of the capsular type of the p. multocida strains isolated from sheep pneumonia in iran. bacteriological and bio...

an inactivated trivalent fowl cholera vaccine consisted of serotypes 1, 3 and 4 pasteurella multocida strains was prepared. the vaccine provided 70-100% protection against challenge with homologous starins. elisa assay showed a considerable increase in antibody titer after towice vaccination of 8 weeks chickens. it was found that the trivalent vaccine can induce immunogenic response in vaccinat...

Pasteurella multocida (P. multocida) is an important pathogen of various domestic animals. The outer membrane proteins (OMPs) play a major role in pathogenesis and immunogenicity of P. multocida. The aim of the study was to develop indirect enzyme linked immuno sorbant assay (ELISA) based on OMPs to ascertain the antibody titers in animals post-infection or to gauge the potency of vaccine. The ...

OBJECTIVE The rate of infection following cat bites appears to be greater than that from dog bites. To study the clinical picture, complications and microbiology (in humans and cats), this prospective study was performed. METHODS A prospective study with patients with clinical symptoms of infection due to cat bites from three emergency wards during two years in Stockholm, Sweden. Aerobic and ...

Pasteurella multocida causes sporadic or epidemic diseases among different animal species, including focal and systemic infections in humans. Penicillin is the drug of choice for treatment of Pasteurella infections, but third-generation cephalosporins and fluoroquinolones are a good alternative for betalactamase-producing strains or for allergic patients (1, 10). Quinolone resistance in gram-ne...

A new macrolide antibiotic, EL-870, 20-deoxo-20-(3,5-dimethylpiperidin-1-yl)desmycosin, has been prepared by chemical modification of desmycosin. In vitro, against selected animal bacterial pathogens, it inhibited growth of Pasteurella multocida, Pasteurella haemolytica, Mycoplasma hyopneumoniae, Actinobacillus pleuropneumoniae, Streptococcus suis, Actinomyces pyogenes and certain other bacteri...