نتایج جستجو برای: autoimmune liver disease

تعداد نتایج: 1763327  

Journal: :iranian journal of allergy, asthma and immunology 0
ghasem mosayebi molecular and medicine research center, department of immunology, school of medicine, arak university of medical sciences, arak, iran and department of immunology, faculty of medical sciences, tarbiat modares university, tehran, iran seyed mohammad moazzeni department of immunology, faculty of medical sciences, tarbiat modares university, tehran, iran

dendritic cells (dcs) play an important role in induction of cellular immune responses. it seems that dcs that reside in different organs may be distinct in their ability to  induce immune responses. this study was done to address the differences between spleen and liver dcs in induction of immune response and/or tolerance. cd11c+  dcs were separated from the liver and spleen of c57bl/6 mice an...

Journal: :Orphanet Journal of Rare Diseases 2008
Teru Kumagi E Jenny Heathcote

Primary biliary cirrhosis (PBC) is a chronic and slowly progressive cholestatic liver disease of autoimmune etiology characterized by injury of the intrahepatic bile ducts that may eventually lead to liver failure. Affected individuals are usually in their fifth to seventh decades of life at time of diagnosis, and 90% are women. Annual incidence is estimated between 0.7 and 49 cases per million...

Journal: :Current gastroenterology reports 2016
Craig Lammert Veronica M Loy Kiyoko Oshima Samer Gawrieh

Autoimmune hepatitis (AIH) is a complex autoimmune disease characterized by immune-mediated destruction of hepatic parenchyma which can result in cirrhosis, liver failure, and death. Current American Association for the Study of Liver Diseases (AASLD) and European Association for the Study of Liver (EASL) guidelines recommend corticosteroids alone or in combination with azathioprine as first-li...

Journal: :Archives of disease in childhood 1997
H V Melendez M Rela A J Baker C Ball B Portmann G Mieli-Vergani N D Heaton

Giant cell hepatitis (CGH) with autoimmune haemolytic anaemia (AHA) is a distinct entity with an aggressive course. Immunosuppression may help early disease. A case is reported of a child with GCH and AHA with early disease recurrence after liver transplantation for end stage liver disease.

Journal: :Annals of hepatology 2013
Francesco Tovoli Antonio Vannini Marco Fusconi Magda Frisoni Daniela Zauli

Autoimmune liver diseases (AILD) are a group of immunologically induced hepatic disorders that can lead to liver cirrhosis and end-stage liver disease. Extra-hepatic involvement and association with rheumatic diseases (such as Sjögren's syndrome, systemic sclerosis and rheumatoid arthritis) are well known, whereas the coexistence of AILD with small-vessel vasculitis in the same patients have be...

2011
Sukran Erten Aylin Demirezer Bolat Fatma Ebru Akin Osman Ersoy

Systemic lupus erythematosus (SLE) is an autoimmune disease with unknown etiology. Although liver dysfunction is rare in SLE, 25 - 50% of patients may develop abnormal liver functions. Here, we described a case presented as fulminant hepatitis and diagnosed as SLE.

2012
Toru Wakamatsu Tatsuo Kanda Akinobu Tawada Tatsuo Miyamura Masanori Takahashi Tetsuhiro Chiba Makoto Arai Hitoshi Maruyama Keiichi Fujiwara Fumio Imazeki Osamu Yokosuka

Antimitochondrial antibody (AMA) is one of the representative features of primary biliary cirrhosis (PBC). PBC is a female-dominant disease usually presenting intrahepatic bile duct destruction, cholestasis and fibrosis with or without chronic nonsuppurative destructive cholangitis. We presented the case of a 63-year-old man with acute liver failure who had AMA, pronounced alanine aminotransfer...

2011
Michael Hunter Maurice B Loughrey Moyra Gray Peter Ellis Neil McDougall Michael Callender

AIMS Overlap syndromes constitute a significant proportion of autoimmune liver disease. Our aim was to describe our cohort and evaluate practical methods of correctly diagnosing autoimmune hepatitis/primary sclerosing cholangitis overlap syndrome as early as possible clinically. METHODS 118 autoimmune hepatitis patients were screened for cholestatic liver function tests. 24 patients with chol...

2015
Maxime Dauvergne Anissa Moktefi Marion Rabant Cécile Vigneau Tomek Kofman Stephane Burtey Christophe Corpechot Thomas Stehlé Dominique Desvaux Nathalie Rioux-Leclercq Philippe Rouvier Bertrand Knebelmann Jean-Jacques Boffa Thierry Frouget Eric Daugas Mathieu Jablonski Karine Dahan Isabelle Brocheriou Philippe Remy Philippe Grimbert Philippe Lang Oliver Chazouilleres Dil Sahali Vincent Audard Patel. Sanket

The association between membranous nephropathy (MN) and immunological disorder-related liver disease has not been extensively investigated, and the specific features of this uncommon association, if any, remain to be determined.We retrospectively identified 10 patients with this association. We aimed to describe the clinical, biological, and pathological characteristics of these patients and th...

Journal: :Scandinavian Journal of Immunology 2023

Liver cytosol antibody type 1 (anti-LC1) is reported to be a marker of 2 autoimmune hepatitis (AIH), liver disease (AILD). However, anti-LC1 not entirely disease-specific, and its clinical value in other hepatic diseases has been well elucidated. Our study aimed explore the associations between diagnoses outcome decompensated cirrhosis or failure (DC/LF) patients positive for anti-LC1. A total ...

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