..........................................................................................v LIST OF FIGURES.................................................................................x INTRODUCTION...................................................................................................1 Definition and Diagnosis of Autism Spectrum Disorder.............................................

In addition to the diagnostic criteria for autism spectrum disorder, a number of clinically important comorbid complaints, including sensory abnormalities, are also discussed. One difference often noted in these accounts is hyposensitivity to pain; however, evidence for this is limited. The purpose of the current review therefore was to examine sensitivity to pain of individuals with autism spe...

Social deficits are a core symptom of autism spectrum disorder; however, the perturbed neural mechanisms underpinning these deficits remain unclear. It has been suggested that social prediction errors-coding discrepancies between the predicted and actual outcome of another's decisions-might play a crucial role in processing social information. While the gyral surface of the anterior cingulate c...

Difficulties in emotion perception are commonly observed in autism spectrum disorder. However, it is unclear whether these difficulties can be attributed to a general problem of relating to emotional states, or whether they specifically concern the perception of others' expressions. This study addressed this question in the context of pain, a sensory and emotional state with strong social relev...

Objectives: The theory of mind hypothesis states that children with autism are impaired in the development of the ability to appreciate their own and other people's mental states. The people with Autism Spectrum Disorder needs treatment approach which to strengthen their movement, focus of attention, eye contact and relaxation. "Dohsa-hou" is a Japanese psycho-rehabilitation method by...

Impairment of reciprocal social interaction is a core symptom of autism spectrum disorder. Genetic disorders frequently accompany autism spectrum disorder, such as tuberous sclerosis complex caused by haploinsufficiency of the TSC1 and TSC2 genes. Accumulating evidence implicates a relationship between autism spectrum disorder and signal transduction that involves tuberous sclerosis complex 1, ...

This study examined the effects of a 12-week physical activity intervention on the motor skill proficiency and executive function of 22 boys (aged 9.08 ± 1.75 years) with autism spectrum disorder. In Phase I of the 12 weeks, 11 boys with autism spectrum disorder (Group A) received the intervention, whereas the other 11 boys with autism spectrum disorder (Group B) did not (true control, no inter...

Autism encompasses a broad range of brain disorders that, by conservative estimates, affects 1 in 500 children. Autism-Spectrum Disorders (ASDs) include Asperger’s Syndrome, Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS), Rett Syndrome (which affects only girls) and Autism. Autism Spectrum Disorders impair three main areas of human development: speech, communication and soci...