dr.mirsadraei and colleagues performed an interesting study about the lung hrct findings in chemical warfare patients who suffering from long-term pulmonary complications. they found that air trapping and mosaic attenuation were the most common lung hrct findings. also they divided patients in different clinical entities according to the lung hrct findings (bronchiolitis oblitrans, pulmonary fi...

BACKGROUND AND OBJECTIVE In recent years, the so-called asthma-chronic obstructive pulmonary disease (COPD) overlap syndrome (ACOS) has received much attention, not least because elderly individuals may present characteristics suggesting a diagnosis of both asthma and COPD. At present, ACOS is described clinically as persistent airflow limitation combined with features of both asthma and COPD. ...

the process of bronchial tissue repair/remodeling depends on balance between production and degradation achieves the regulation of extracellular matrix turnover. we designed this study to evaluate relation between transforming growth factor β1 (tgfβ1) and tissue inhibitory of metaloproteinase 2 (timp2) as two main tissue mediators on activity and reversibility of asthma and chronic obstructive ...

BACKGROUND Prior work suggests that asthma-COPD overlap syndrome (ACOS) has a greater health burden than asthma alone or COPD alone. In the current study, we have further evaluated the health burden of ACOS in a nationally representative sample of the US population, focusing on patient-reported outcomes and health care utilization and on comparisons with asthma alone and COPD alone. Patient-rep...