The trend towards natural products in the world is increasing due to increased drug resistance of infectious diseases, high prices for drugs and difficulty access. Also, bacterial or viral diseases that are difficult treat need a long time proper treatment cause important infections people. Since effective could not be developed most infections, it very find against viruses introduce them scien...

Hydroxyapatite-tricalcium phosphate (HA-TCP) scaffold is a three-dimensional structure used to support bone regeneration. Ideally, the should be biocompatible, biodegradable, and non-toxic. The tissue engineering technique uses combined stem cell repair defect. To prove non-toxic properties of scaffold, cytotoxicity test needed for human umbilical cord mesenchymal (HUCMSCs). In this study, 27 s...

Objective : The anti-tumor effect of the beta-adrenergic receptor antagonist propranolol in breast cancer is well known; however, its activity glioblastoma not well-evaluated. Notch-Hes pathway known to regulate cell differentiation, proliferation, and apoptosis. We investigated human lines, role Notch Hes signaling this process.Methods performed immunohistochemical staining on 31 surgically re...

AIM The present study was conducted to survey the potential cytotoxic influence of freeze-dried aqueous extract of its fruits on gastrointestinal cell lines, namely AGS (human gastric carcinoma) and KYSE30 (human esophageal squamous cell carcinoma. BACKGROUND Rosemary (Rosmarinus officinalis) is a wild medicinal plant shown to have anticancer activity. Carnosic and rosmarinic acids are compou...

Liver cancer has become one of the major types of cancer with high mortality and liver cancer is not responsive to the current cytotoxic agents used in chemotherapy. The purpose of this study was to examine the in vitro cytotoxicity of goniothalamin on human hepatoblastoma HepG2 cells and normal liver Chang cells. The cytotoxicity of goniothalamin against HepG2 and liver Chang cell was tested u...

Psidium guajava (Guava) could be an ancient remedy used for a variety of health conditions. Research suggests that guava fruits and leaves might have advantages. Guava is the tropical tree with yellowish-green skin fruits, widely grown in Central America Asia. Individuals use leaf tea as treatment gastric symptoms many countries, together India China. In different like Mexico, individuals histo...

Promotion of Apoptosis Does Not Necessarily Mean Inhibition of Remodeling To the Editor: Hypoxic pulmonary hypertension is a serious disease characterized by hypoxic pulmonary vasoconstriction and pulmonary vascular remodeling. In the article “The MicroRNA-328 Regulates Hypoxic Pulmonary Hypertension by Targeting at Insulin Growth Factor 1 Receptor and l-Type Calcium Channel-1C,” the authors ha...

introduction: this in vitro study assessed and compared the cytotoxicity of mineral trioxide aggregate (mta), calcium-enriched mixture (cem) cement, biodentine (bd) and octacalcium phosphate (ocp) on stem cells of the human apical papilla (scap). methods and materials: scaps were isolated from two semi-impacted third molars. the cells were cultured in wells of an insert 24-well plate and were t...