Some oxadiazole derivatives were tested in vitro against Aspergillus parasiticus, Aspergillus flavus, Aspergillus niger, Fusarium solani, Fusarium moniliforme and Stachybotrys chartarum. All compounds showed the highest antifungal activity against S. chartarum. Among these compounds (3a-j), compounds 3a, 3c, 3d, 3e, 3i, 3j exhibited the same level of antifungal activity against all tested mold ...

aspergillus species (a flavus and a niger) are important sources of inhalant allergens. current  diagnostic  modalities  employ  crude  aspergillus  extracts  which  only  indicate  the source to which the patient has been sensitized, without identifying the number and type of allergens in crude extracts. we report a study on the identification of major and minor allergens of the two common air...

Section Terrei of Aspergillus was studied using a polyphasic approach including sequence analysis of parts of the β-tubulin and calmodulin genes and the ITS region, macro- and micromorphological analyses and examination of extrolite profiles to describe three new species in this section. Based on phylogenetic analysis of calmodulin and β-tubulin sequences seven lineages were observed among isol...

Culture-based methods were employed to recover 3929 isolates of fungi from soils collected in May and July 2014 from mound nests of Formica ulkei and adjacent non-nest sites. The abundance, diversity, and richness of species from nest mounds exceeded those of non-mound soils, particularly in July. Communities of fungi from mounds were more similar to those from mounds than non-mounds; this was ...

Monoclonal antibodies (mAbs) due to their binding specificity, their homogeneity and great ability to be produced in unlimited quantities are important reagent in diagnosis and treatment of diseases like infections and cancers. Hybridoma cell lines grown as ascites tumours in Pristane primed mice will frequently yield milligram quantities of monoclonal antibody per milli liter of ascites fluid....

Pu-erh tea originates from the province of Yunnan in south-western China. As this tea is produced by so called Aspergillus post-fermentation the question arises which molds and mycotoxins may be found in this tea. In total 36 samples of Pu-erh tea were investigated for their content of filamentous fungi and the mycotoxins aflatoxins B1, B2, G1, and G2, fumonisins B1, B2, and B3, and ochratoxin ...

Fungi of the genus Aspergillus are widespread in the environment. Some Aspergillus species, most commonly Aspergillus fumigatus, may lead to a variety of allergic reactions and life-threatening systemic infections in humans. Invasive aspergillosis occurs primarily in patients with severe immunodeficiency, and has dramatically increased in recent years. There are several factors at play that con...

Invasive aspergillosis caused by Aspergillus species (Aspergillus fumigatus, A. flavus, and A. terreus) is life-threatening infections in immunocompromised patients. Understanding the innate and adaptive immune response particularly T-helper cells (TH-cells) against these Aspergillus species and how the different sub-set of TH-cells are regulated by differentiating cytokines at primary target o...

The aim of this study was to determine the mycoflora of poultry feeds and evaluate the aflatoxin and ochratoxins producing ability of isolated Aspergillus species. One hundred and nineteen samples of commercially prepared and farm mixed feeds were collected during 20052007. The samples were inoculated on potato dextrose agar, Czapek dox solution agar, Czapek yeast autolysate agar and yeast extr...

Aspergillus fumigatus, a common mold, rarely infects humans, except during prolonged neutropenia or in cases of chronic granulomatous disease (CGD), a primary immunodeficiency caused by mutations in the NADPH oxidase that normally produces fungicidal reactive oxygen species. Filamentous hyphae of Aspergillus are killed by normal, but not CGD polymorphonuclear leukocytes (PMN); however, the few ...