BACKGROUND Extensive epidemiologic studies have shown that cardiovascular disease and the metabolic syndrome (MetS) are associated with serum concentrations of liver enzymes; however, fundamental characteristics of this relation are currently unknown. OBJECTIVE We aimed to explore the role of liver aminotransferases in nonalcoholic fatty liver disease (NAFLD) and MetS. DESIGN Liver gene- an...

background: garcinia kola seed is consumed indiscriminately in nigeria without recourse to its potential toxicity. therefore, this study was aimed at assessing the toxicity of the aqueous extract of g. kola seeds on selected tissues of male rats.  methods: thirty male rats (215.00 ± 18.58 g) were assigned into four groups: a, b, c and d which received 0.5 ml of distilled water, 25, 50 and 100 m...

background: hepatitis e virus (hev) infection is a self-limiting viral infection that can lead to severe complications and death. in different regions the epidemiology of this infection varies. in this study we evaluated the seroepidemiology of hepatitis e infection in jahrom, a city in southern iran. methods: this was a cross-sectional descriptive study of serum samples from 477 subjects, incl...

conclusions elevation of liver enzymes appears in 29 % obese children in a tertiary care centre. absolute alanine aminotransferase levels are significantly higher in obese than in overweight children. even obese children with normal liver enzymes show signs of fatty liver disease as demonstrated by liver enzymes at the upper limit of normal. results elevated alanine aminotransferase was observe...

Introduction: There is little evidence of potential hepatotoxicity of Remdesivir (RDV), in vitro. Regarding the effective results of RDV in patients with COVID-19 and the impact of COVID-19 on liver function, we investigated the effects of RDV on the expression and activity of liver enzymes in chicken embryo-derived hepatocytes. Material and Methods: In this in vitro study, 20 embryonated chic...

INTRODUCTION Plasma antioxidant vitamins (retinol, α-tocopherol, β-carotene) were measured to establish the influence of clinical condition and mycophenolate mofetil (MMF) treatment on the nutritional status of renal transplant recipients. MATERIAL AND METHODS In 106 adult patients plasma vitamins were measured and 24-h diet history questionnaires were conducted. The MMF influence on plasma v...

BACKGROUND AND PURPOSE Major hepatotropic viruses continue to be important causes of acute viral hepatitis in developing countries. This work was carried out to detect the seroprevalence of hepatitis E virus (HEV) markers in children with acute viral hepatitis due to hepatotropic viruses (A, B and C) and non-A, non-B, non-C acute hepatitis, and to ascertain the influence of HEV superinfection i...