Background: 7-LiF: Mg,Cu,P (GR-207A) is one kind of thermo-luminescent dosimeters (TLD) which can be used in diagnostic radiology and radiotherapy applications. Because of having suitable properties such as good sensitivity, small size and being tissue equivalent, thermo-luminescent dosimetry has been one of the most important techniques in medicine over many years. Choosing a correct energy fo...

Background: Gold nanoparticles (GNPs) have been shown as a good radiosensitizer. In combination with radiotherapy, several studies with orthovoltage X-rays have shown considerable dose enhancement effects. This paper reports the dose enhancement factor (DEF) due to GNPs in 18 megavoltage (MV) beams. Materials and Methods: Different geometrical 50-nm GNPs configurations at a concentrati...

Treating shallow tumors with a homogeneous dose while simultaneously minimizing the dose to distal critical organs remains a challenge in radiotherapy. One promising approach is modulated electron radiotherapy (MERT). Due to the scattering properties of electron beams, the commercially provided secondary and tertiary photon collimation systems are not conducive for electron beam delivery when s...

Purpose: To improve the accuracy in megavoltage photon beam dose calculation in CBCT-based radiation treatment (RT) plans, using a kilovoltage cone-beam computed tomography (CBCT)-todensity-step (CBCT-SF) function. Materials and Methods: The CBCT-SF table is constructed from differential histograms of the voxel values of CBCT and Fan-beam CT (FBCT). From the CBCT histograms, frequency peaks rep...

This paper reviews the mathematical formalism of the least squares template matching (LSM) and presents a framework for automatic quality control of the resulting match. LSM is an iterative and area-based fitting method which replaces the conventional multi-step procedure of feature extraction followed by discrete parameter search. The technique is especially suitable for attaining very high pr...

PURPOSE Active matrix flat-panel imagers (AMFPIs) incorporating thick, segmented scintillators have demonstrated order-of-magnitude improvements in detective quantum efficiency (DQE) at radiotherapy energies compared to systems based on conventional phosphor screens. Such improved DQE values facilitate megavoltage cone-beam CT (MV CBCT) imaging at clinically practical doses. However, the MV CBC...

We present a case of cervical cancer treated by concurrent chemoradiation. In radiation therapy part, the combination of the whole pelvic helical tomotherapy plus image-guided brachytherapy with megavoltage computed tomography of helical tomotherapy was performed. We propose this therapeutic approach could be considered in a curative setting in some problematic situation as our institution.