This study aims to investigate how lighting design can be used as an environmental design feature within historic sites in cities to turn a space into a place through placemaking processes. Accordingly, the research question is: What artificial lighting design aspects need to be taken into account in historic sites within cities through a placemaking process? Naghshe-Jahan Square’s in Isfahan, ...

Insects, fish, and amphibians undergo the intriguing process of metamorphosis. Metamorphic processes are governed by gene regulatory networks: complex networks of gene-protein interactions. Recent studies demonstrate the isolated use of artificial gene regulatory networks for (1) body development, (2) metamorphosis, or (3) epigenetics. We will evolve a gene regulatory network by fitness uniform...

Shift work which causes circadian disruption is an established cancer risk factor. A large body of experimental and epidemiological data proves that exposure to light at night promotes carcinogenesis in various tissues and accelerates aging [1-3]. Artificial or natural light through master clock located in suprachiasmatic nuclei of hypothalamus suppresses night peak of melatonin synthesis in th...

Due to its disruptive effects on circadian rhythms and sleep deprivation at night, shiftworking is currently recognized as a risk factor for breast cancer (BC). As revealed by the present analysis based on a comparative case-control study of 1679 women, exposure to light-at-night (LAN) in the "sleeping habitat" is significantly associated with BC risk (odds ratio [OR] = 1.220, 95% confidence in...

The population of artificial satellites and space debris orbiting the Earth imposes non-negligible constraints on both operations ground-based optical radio astronomy. ongoing deployment several satellite `mega-constellations' in 2020s represents an additional threat that raises significant concerns. expected severity its unwanted consequences is still under study, including interference inform...