OBJECTIVE Candida albicans biofilm is frequently found on artificial surfaces and the infections related to biofilm are difficult to eliminate, as they require the removal of artificial devices and treatment with antifungal drugs. Nowadays, fungal growth in biofilms is difficult to eradicate with conventional antifungal drugs such as fluconazole. Among chelating agents, disodium salt-Ethylene D...

The potential role of nanotechnologies in the future of psychiatry. A systematic review. Abstract. Nanomedicine is defined as the area using nanotechnology's concepts for the benefit of human beings' health and well being. In this article, we aimed to provide an overview of areas where nanotechnology is applied and how they could be extended to care for psychiatric illnesses. The main applicati...

Abstract Background Identifying novel therapeutic targets is crucial for the successful development of drugs. However, cost to experimentally identify huge and only approximately 400 genes are FDA-approved As a result, it inevitable develop powerful computational tools that can potential targets. Fortunately, human protein-protein interaction network (PIN) could be useful resource achieve this ...

BACKGROUND Continuous deep sedation until death is a highly debated medical practice, particularly regarding its potential to hasten death and its proper use in end-of-life care. A thorough analysis of important trends in this practice is needed to identify potentially problematic developments. This study aims to examine trends in the prevalence and practice characteristics of continuous deep s...

Aaron Kesselheim and colleagues examine potential strategies to promote greater prescribing of generic drugs and follow-on biologics.

nowadays apphcanon of nanotubes in biology and medicinal science is more investigated. nanotubes can passthroueh cell walls and transport and release drugs in special tissues. the purpose of this paper is to investigatethe interaction of a nanotube having hydroxyl functional groups (oh) with an anticancer agent. in this worktransporting of an anticancer drug named 2-(2-amino 6,7-dimethyl pterid...

conclusions our results suggested that the prevalence of prescription drugs, alcohol and illicit substance use was relatively low, though still significant, among iranian students, which was strongly associated with family and friends’ use. the findings of this research can be used for planning and evaluating interventions by considering the risk factors and protective factors in universities. ...