The cingulum bundle (CB) is one of the brain's major white matter pathways, linking regions associated with executive function, decision-making, and emotion. Neuroimaging has revealed that abnormalities in particular locations within the CB are associated with specific psychiatric disorders, including depression and bipolar disorder. However, the fibers using each portion of the CB remain unkno...

A 2D Navier-Stokes solver was developed to simulate steady,laminar flow over a backward-facing step of height h. The step expansion ratio=1/2 and the flow at the step was assumed to be fully developed, laminar channel flow. The Reynolds number for this flow was defined as Re=Uh/ν. The 2D incompressible Navier-Stokes equations was solved in generalized curvilinear coordinates using artificial co...

where B = ( B1, · · · ,Bd ) is a standard Brownian motion, and Cb ( RN;RN ) denotes the set of RN-valued smooth functions defined over RN whose derivatives of any order are bounded. In particular, we will use the classical notation V f (x) = ∑N i=1 V i (x) ( ∂ f/∂xi ) (x) for V ∈ Cb (RN;RN) and f a differentiable function from Rn into R. This stochastic differential equation can be written in I...

In this study, we focused on the pharmacological characterization of cannabinoid receptor coupling to G protein-gated inwardly rectifying potassium (GIRK) channels. Cannabinoids were tested on Xenopus laevis oocytes coexpressing the CB(1) receptor and GIRK1 and GIRK4 channels (CB(1)/GIRK1/4) or the CB(2) receptor and GIRK1/4 channels (CB(2)/GIRK1/4). WIN 55,212-2 enhanced currents carried by GI...