نتایج جستجو برای: articular chondrocyte
تعداد نتایج: 32509 فیلتر نتایج به سال:
OBJECTIVE To study the effects of intra-articular injection of magnesium sulfate (MgSO(4)) on the development of osteoarthritis (OA) and to examine concomitant changes in the nociceptive behavior of rats. METHODS OA was induced in Wistar rats with intra-articular injection of collagenase (500 U) in the right knee; the left knee was left untreated. In the OA+MgSO(4) group (n=7), the treated kn...
BACKGROUND An intra-articular injection of local anesthetics is a common procedure for diagnostic and therapeutic purposes. It has been shown that these agents are toxic to articular cartilage and synovial tissue in a dose- and time-dependent fashion, and in some cases, they may lead to postarthroscopic glenohumeral chondrolysis (PAGCL). However, the role of apoptosis in cell death is still unc...
Introduction: The mechanical environment of the chondrocyte is one of several important environmental factors which influence the normal balance between synthesis and degradation of the articular cartilage extracellular matrix (ECM). Previous studies have shown that compression of cartilage explants alters cellular metabolism in a timeand spatially-varying manner which is correlated with the lo...
The limited healing capability of articular cartilage has primarily been associated with changes in chondrocyte phenotype. Chondrocytes, resident cells in articular cartilage, are responsible for the control of extracellular matrix turnover. On the other hand, ECM homeostasis plays important role in ensuring appropriate cartilage tissue function. Hence, to achieve this state of balance, 2 diffe...
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